Long-term evaluation of a device for enlarged prostate treatment

Prospective, Open-Label, Non-Comparative, Study to Assess the Long Term Safety and Efficacy of Butterfly Medical Prostatic Retraction Device in Benign Prostatic Hyperplasia (BPH) Patients Who Completed 12 Months of Follow-Up Post Implantation (Continuation Study for Study BM-011-IL)

Not applicable Interventional Butterfly Medical Ltd. · NCT05330520

This study is testing a new device for treating an enlarged prostate to see how safe and effective it is for men with BPH over a period of up to five years.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages50 Years to 80 Years
SexMale
SponsorButterfly Medical Ltd. Industry-sponsored
Locations2 sites (Petah Tikva and 1 other locations)
Trial IDNCT05330520 on ClinicalTrials.gov

What this trial studies

This study evaluates the long-term safety and efficacy of the Butterfly Medical Prostatic Retraction Device in patients with Benign Prostatic Hyperplasia (BPH) who have completed 12 months of follow-up after implantation. Participants will be monitored for up to 5 years, with assessments including safety events, urinary flow tests, residual urine measurements, and International Prostate Symptom Score (IPSS) questionnaires. Additionally, the study will assess the impact of the device on sexual quality of life.

Who should consider this trial

Good fit: Ideal candidates are men who have completed 12 months of follow-up in the previous study BM-011-IL and are willing to continue participating.

Not a fit: Patients who did not complete the 12 months follow-up in the previous study will not benefit from this continuation study.

Why it matters

Potential benefit: If successful, this study could provide a safer and more effective treatment option for men suffering from BPH and its associated symptoms.

How similar studies have performed: While this approach is based on previous studies, the long-term evaluation of this specific device is novel and has not been extensively tested.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Completed 12 months follow up under study BM-011-IL. A subject that missed one or more visits during BM-011-IL will be included, as long as the subject has collected data at 12 months follow up visit.
2. Provide signed informed consent to the continuation study and be willing and able to perform follow up visits and activities as described in the study protocol.

Exclusion Criteria:

1\. Patients which participated in the BM-011-IL study and did not complete 12 months follow up visit under study BM-011-IL due to any reason

Where this trial is running

Petah Tikva and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions BPHBOO - Bladder Outflow ObstructionEnlarged ProstateLUTSUrinary obstructionRetrograde ejaculation
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.