Long-term effects on children who received stem cell transplants
Longitudinal Evaluation of Recipients of Hematopoietic Stem Cell Transplantation (HSCT)
Stanford University · NCT01629017
This study looks at the long-term health of children and young adults who had stem cell transplants to see how they can be better cared for in the future.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 800 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Stanford University (other) |
| Locations | 1 site (Stanford, California) |
| Trial ID | NCT01629017 on ClinicalTrials.gov |
What this trial studies
This project systematically collects and analyzes long-term clinical data from children, adolescents, and young adults who have undergone hematopoietic stem cell transplantation (HSCT). The study aims to establish guidelines for long-term follow-up care and create a comprehensive database to monitor late effects of HSCT. By conducting periodic examinations and collecting blood and tissue samples, the research seeks to identify potential complications early and improve survivor health outcomes through education and intervention.
Who should consider this trial
Good fit: Ideal candidates include children, adolescents, and young adults who are scheduled to receive or have received a hematopoietic stem cell transplant.
Not a fit: Patients who have relapsed from a malignant diagnosis post-HSCT and are not being considered for a new transplant may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could enhance the long-term health management of HSCT survivors by identifying and preventing complications.
How similar studies have performed: Other studies have shown success in long-term follow-up care for HSCT survivors, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Participant is scheduled to receive OR has received a hematopoietic stem cell transplant (HSCT) for any condition. * Participant may have had a HSCT in another institution than Lucile Packard Children's Hospital (LPCH) yet has transferred follow-up long-term care to our institution and is being seen through the late-effects clinic from the Pediatric HSCT program. * Participant AND/OR parent/legally authorized representative is able to provide written informed consent and assent (as applicable) for participation. Exclusion Criteria: * Participant has relapsed from a malignant diagnosis post HSCT and is not being worked-up for a new HSCT. * Participant or patient's authorized guardian is unable to provide consent and assent
Where this trial is running
Stanford, California
- Stanford University School of Medicine — Stanford, California, United States (RECRUITING)
Study contacts
- Principal investigator: Ami Shah — Stanford University
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Blood and Marrow Transplant