Live and Interactive Fitness Training Program for Knee Osteoarthritis
Improving Physical Function and Quality of Life in Adults With Knee Osteoarthritis Utilizing an Online Live and Interactive Fitness Training Program (Vivo Knee OA)
This study is testing if a live online exercise program can help people aged 55-85 with knee osteoarthritis feel better and improve their health compared to regular home exercises.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 334 (estimated) |
| Ages | 55 Years to 85 Years |
| Sex | All |
| Sponsor | Intermountain Health Care, Inc. Academic / other |
| Locations | 1 site (Murray, Utah) |
| Trial ID | NCT06462560 on ClinicalTrials.gov |
What this trial studies
This clinical trial evaluates the effectiveness of a live online exercise program called Vivo for patients with knee osteoarthritis. Participants aged 55-85 will be randomized into two groups: one receiving the Vivo program twice a week for six months and the other receiving usual care with a home exercise program. The study will assess various outcomes, including functional assessments, quality of life, and exercise self-efficacy at multiple time points over a year. The goal is to determine if the Vivo program can improve symptoms and overall health in this population.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 55-85 with symptomatic knee osteoarthritis and a BMI between 20-34.9.
Not a fit: Patients with neurological conditions affecting function or those not meeting the inclusion criteria may not benefit from this study.
Why it matters
Potential benefit: If successful, this program could significantly enhance the quality of life and functional abilities of patients suffering from knee osteoarthritis.
How similar studies have performed: Previous studies have shown positive outcomes with similar online exercise interventions for osteoarthritis, indicating potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria:
* 55-85 years of age
* Diagnosis of Osteoarthritis within the prior 6 months
* Symptomatic OA defined as self-report:
* Pain in the knee(s) on most days of the month
* Difficulty with at least one of the following because of knee pain:
* walking ¼ of a mile
* climbing stairs
* getting in and out of a car, bath, or bed
* rising from a chair
* or performing shopping, cleaning, or self-care activities
* Radiographic KL grade II-III (using Kellgren and Lawrence criteria) of one or both knees
* Physically able to participate in strength training - able to do one chair stand unassisted in order to test change in 30-second chair stand
* Ambulatory and community-dwelling
* Sedentary or insufficiently active as measured by the PAVS
* Access to Wi-Fi in defined exercise space
* BMI of 20-34.9 kg/m2
* Document medication specific to OA and knee pain
* Willing and able to provide consent
Exclusion Criteria:
* Neurological conditions causing functional impairments (Parkinson's disease, MS, ALS)
* Diagnosis of dementia
* Inability to complete ≥1 ADLs without assistance.
* Knee surgery in the past 6 months
* Severe osteoporosis T-score \< -3.5
* No concurrent enrollment in physical therapy for knee pain
* No concurrent enrollment in the Intermountain Arthrofit program
* Under the age of 55 or ≥85
* Asymptomatic OA
* Not having knee pain or having significant knee pain (WOMAC Pain score of ≤3 or ≥18)
* KL Grade 1 or 4
* BMI above 34.9 kg/m2 or ≤20 kg/m2
* Participation in formal strength training more than 30 minutes a week in the past 6 months.
* PAVS - Participating in 150 minutes per week of moderate intensity physical activity or 75 minutes of vigorous intensity activity, or an equivalent combination of moderate and vigorous intensity physical activity.
* Co-morbid disease that would threaten safety or impair ability to participate in a live and interactive strength training program
* Symptomatic or severe coronary artery disease; peripheral vascular disease
* Untreated hypertension
* Active cancer other than skin cancer
Where this trial is running
Murray, Utah
- Intermountain Health — Murray, Utah, United States (Recruiting)
Study contacts
- Principal investigator: Anthony Beutler, MD — Intermountain Health
- Study coordinator: Amelia Millward
- Email: amelia.millward@imail.org
- Phone: 801-507-8095
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.