Listening to music during breast surgery may reduce propofol use

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center, randomized study compares two groups: one listens to music through headphones during anesthesia and recovery, the other receives standard anesthesia care without music. All participants receive the same total intravenous anesthesia protocol and BIS monitoring to gauge anesthesia depth. The primary outcome is total propofol consumption (mg/kg), with secondary outcomes including BIS values, remifentanil use, vital signs, recovery room stay, postoperative nausea and vomiting, and patient satisfaction.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age between 18 and 70 years
* American Society of Anesthesiologists physical status I or II
* Scheduled to undergo elective breast surgery with an estimated surgical duration of 45 to 180 minutes
* Planned anesthesia technique is total intravenous anesthesia
* Able to understand Turkish and communicate verbally
* Able to read and write and provide written informed consent
* Clinically normal hearing function and no ear, nose, or throat condition that prevents headphone use

Exclusion Criteria:

* Diagnosed unilateral or bilateral hearing loss or use of a hearing aid
* Current psychiatric disease or regular use of psychotropic medication, including antidepressants, antipsychotics, anxiolytics, or hypnotics
* Diagnosis of chronic pain syndrome or chronic use of opioids, pregabalin, or gabapentin
* Neurological disease that may affect BIS interpretation, such as epilepsy, dementia, stroke sequelae, or Parkinson disease
* Known allergy or contraindication to propofol, remifentanil, or rocuronium
* Morbid obesity, defined as body mass index greater than 40 kg/m²
* History of active alcohol or substance dependence
* Pregnancy or breastfeeding
* Emergency surgery or reoperation
* Planned addition of regional anesthesia in the preoperative period
* Refusal to participate in the study or refusal to sign the informed consent form

Where it's running

• Bursa Uludag University Faculty of Medicine
  Bursa, Bursa, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Selcan Akesen, MD
• Email: selcanakesen@uludag.edu.tr
• Phone: +90 224 295 32 74

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.