Clinical trial Recruiting at 1 site Interventional Ages 18 to 65

Liquid vitamin C and glutathione sachets for skin health

Official title: Efficacy Evaluation Study of Vitamin C and Glutathione Liquid Sachet

Run by TCI Co., Ltd. · NCT07379216 · Data updated 2026-11-12

This test tries whether daily liquid vitamin C plus glutathione sachets improve skin appearance and reduce oxidative stress in healthy adults aged 18–65.

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Quick facts

Study typeInterventional
Ages18 Years to 65 Years
SexAll
Enrollment30 (estimated)
SponsorTCI Co., Ltd.
Industry-sponsored
Locations1 site (Pingtung City)
StatusRecruiting
StartedJanuary 24, 2026
Main results expectedMay 18, 2026
Study endsJune 1, 2026
Registry record updatedFebruary 4, 2026
Trial IDNCT07379216 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy adults 18–65 without dermatologic or systemic disorders, able to avoid other comparable products and attend study visits, are the intended participants.

Probably not a fit

Individuals with obvious skin surface damage, recent facial laser/peeling, current skin-affecting medications, known allergies to the ingredients, or who are pregnant or breastfeeding are unlikely to benefit or be eligible.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, double-blinded, placebo-controlled, parallel trial of daily liquid vitamin C and glutathione sachets taken for 12 consecutive weeks. Healthy adults aged 18–65 will be randomized to active or placebo and asked to avoid other skin-active products during the study. Skin measurements and self-assessment questionnaires will be collected at baseline and at 4, 8, and 12 weeks, with fasting blood samples at baseline and week 12 to measure antioxidant markers. The trial aims to link objective skin measurements and blood antioxidant changes to supplementation over a three-month period.

Why it matters

Potential benefit: If successful, the supplements could modestly improve skin condition and lower markers of oxidative stress over a 12-week period.

How similar studies have gone: Prior small trials and observational studies have reported antioxidant and cosmetic skin effects from vitamin C or glutathione, but high-quality randomized data remain limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy male or female adults, aged 18-65 years old;
* Commitment not to use products having activity comparable with that of the product to be tested during the study period;
* Free of any dermatological or systemic disorder that would interfere with results.

Exclusion Criteria:

* Subject with obvious skin surface damage;
* Subject who had oral or topical medication which may affect skin condition within 1 month;
* Individuals with known allergies to cosmetics, medications, or foods (especially those allergic to legumes/soy);
* Pregnant or breastfeeding individuals;
* Received facial laser therapy, chemical peeling in the past 2 months.
* Individuals unwilling to allow publication or public disclosure of photographs taken as part of the study results

Where it's running

  • Chia Nan University of Pharmacy & Science
    Pingtung City, Taiwan
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.