Lip product with Caulerpa lentillifera extract to reduce dark lips
The Effectiveness of a Novel Lip Product Containing Caulerpa Lentillifera Extract for Reducing Lip Hyperpigmentation
We will test if a lip product containing Caulerpa lentillifera extract can reduce darkened lips in Thai adults aged 18–60 who are concerned about lip pigmentation.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Chulalongkorn University Academic / other |
| Locations | 1 site (Bangkok) |
| Trial ID | NCT07067879 on ClinicalTrials.gov |
What this trial studies
Adults with self-reported darkened lips will apply the investigational lip product twice daily for seven days and avoid other lip products during the study. Researchers will compare objective baseline measurements (such as imaging) and participant perceptions before and after the 7-day treatment period. The study is conducted at the Faculty of Dentistry, Chulalongkorn University, with screening to exclude lip abnormalities, recent medication use, or known allergies to the product. Outcomes focus on changes in appearance and subjective perception of lip hyperpigmentation.
Who should consider this trial
Good fit: Thai adults aged 18–60 who are bothered by darkened lips, can refrain from other lip products for seven days, have no lip abnormalities, and have no known allergy to Caulerpa lentillifera or recent medication use.
Not a fit: People with lip malformations, active inflammation or sores, known allergy to Caulerpa lentillifera, or who have taken medications within the prior month are unlikely to benefit from this product.
Why it matters
Potential benefit: If successful, the product could provide a simple, noninvasive cosmetic option to reduce lip hyperpigmentation.
How similar studies have performed: While topical natural extracts have shown limited promise for skin pigmentation generally, using Caulerpa lentillifera specifically for lip hyperpigmentation is relatively novel and has limited prior clinical data.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Understand the study protocol and provide informed consent after being informed of potential risks and benefits. * Refrain from using any other lip products, including lipstick, lip gloss, or lip conditioners, during the study period. Exclusion Criteria: * Have a known allergy or sensitivity to cosmetic products or Caulerpa lentillifera. * Are on medication one month prior to study commencement. * Exhibit lip abnormalities such as malformation, inflammation, swelling, or sores.
Where this trial is running
Bangkok
- Faculty of dentistry, Chulalongkorn university — Bangkok, Thailand (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.