Link between Epstein-Barr Virus and peri-implantitis
Epstein-Barr Virus Implication in Peri-implantitis: Towards an Innovative Etiopathogenic Model Involved in Implant-supported Prostheses Loss.
This study is testing if the Epstein-Barr Virus is linked to peri-implantitis in adults with dental implants to better understand how to treat this condition.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Universitaire de Nice Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Nice) |
| Trial ID | NCT03631849 on ClinicalTrials.gov |
What this trial studies
This study aims to investigate the relationship between the Epstein-Barr Virus and peri-implantitis, a condition that causes inflammation and potential loss of dental implants. Peri-implantitis affects a significant number of patients and is often difficult to diagnose and treat effectively. The research will involve adult patients with at least one dental implant and diagnosed peri-implantitis, as well as a control group of healthy implants. The study will assess the impact of peri-implantitis sanitation surgery and care on the condition.
Who should consider this trial
Good fit: Ideal candidates include adults with at least one dental implant and a diagnosis of peri-implantitis.
Not a fit: Patients with severe hematologic diseases or those with certain chronic illnesses may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and treatment options for patients suffering from peri-implantitis.
How similar studies have performed: While the link between Epstein-Barr Virus and peri-implantitis is suggested by recent studies, this specific approach is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient * Patient with at least one dental implant with a fixed implant-supported prostheses * Patient with a peri-implantitis * (Patient with healthy dental implant for control group) * patients having read and understood the information note on the study and signed the informed consent form. * patients affiliated to the social security system. Exclusion Criteria: * Patient with severe hematologic disease * Patients with previous or current acute illness or severe chronic cardiovascular, renal, hepatic, gastrointestinal, allergic, endocrine, neuro-psychiatric, considered by the investigator to be incompatible with the conduct of the study. * Patients treated with retinoids, oral bisphosphonates, oral anticoagulants or anticonvulsants. * Patient have or have had cancer of the upper aerodigestive tract treated by radiotherapy. * Patient taking a steroidal or non-steroidal anti-inflammatory, anti-cancer or immunosuppressive chemotherapy in the last 6 months. * Patient monitoring considered difficult by the investigator. * Patient with oral dermatitis or adverse occlusion. * Patient with autoimmune disease * Patient with a linguistic or mental incapacity to understand information * Patient trust under curators or judicial protection * Patient participating in another clinical study.
Where this trial is running
Nice
- CHU de Nice — Nice, France (Recruiting)
Study contacts
- Study coordinator: Séverine VINCENT-BUGNAS
- Email: vincent-bugnas.s@chu-nice.fr
- Phone: 0492033270
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.