Link between blood bicarbonate level and risk of ICU admission or death within 48 hours after ER arrival
Statistical Association Between Bicarbonate Levels and Death or Admission to Intensive Care Within 48 Hours in Patients Presenting to the Emergency Department
Centre Hospitalier Departemental Vendee · NCT07340060
This will test whether a patient's bicarbonate level measured on arrival to the emergency department can help predict the risk of death or transfer to intensive care within 48 hours.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 6500 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Centre Hospitalier Departemental Vendee (other) |
| Locations | 1 site (La Roche-sur-Yon) |
| Trial ID | NCT07340060 on ClinicalTrials.gov |
What this trial studies
This is an observational analysis of adult patients who had a blood ionogram on admission to the emergency department at Centre Hospitalier Departemental Vendée. Researchers will compare initial bicarbonate values with short-term outcomes (death or admission to intensive care within 48 hours) using routinely collected clinical data. Statistical models will be used to estimate the strength of the association and adjust for key clinical covariates. No experimental treatments are given and participation requires only that patients consent to use of their clinical data.
Who should consider this trial
Good fit: Adults who present to the emergency department, have a blood ionogram performed at admission, and are able and willing to allow use of their clinical data are the intended participants.
Not a fit: Children, patients who did not have a blood ionogram at admission, or those whose clinical decisions are already guided by more definitive measures may not benefit from this analysis.
Why it matters
Potential benefit: If successful, the finding could help emergency clinicians identify high-risk patients sooner and prioritize monitoring or early interventions.
How similar studies have performed: Prior observational research has linked acid–base abnormalities, including low bicarbonate, with worse short-term outcomes, though predictive value specifically for 48-hour ICU admission or death is not fully established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patient * Patient with blood ionogram performed upon admission to the emergency department * Patient capable of understanding the protocol and not opposed to participating in the research Exclusion Criteria: * NA
Where this trial is running
La Roche-sur-Yon
- Centre Hospitalier Departemental Vendée — La Roche-sur-Yon, France (RECRUITING)
Study contacts
- Principal investigator: COLIN Gwenhael — CHD Vendee
- Study coordinator: Clémentin GABORIAU
- Email: clementin.gaboriau@ght85.fr
- Phone: 0251446572
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Urgency