Light therapy combined with exercise for improving symptoms in Parkinson's disease
Randomized, Double-Blind, Placebo-Controlled Clinical Trial to Evaluate the Effectiveness of Photobiomodulation With Exercise, to Enhance Motor, Cognition and the Quality of Life of Those With Parkinson's Disease
This study is testing if using light therapy along with exercise can help improve symptoms and quality of life for people with moderate Parkinson's disease.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 55 Years to 80 Years |
| Sex | All |
| Sponsor | Gaitway Neurophysio Academic / other |
| Locations | 1 site (Hamilton, Ontario) |
| Trial ID | NCT06036433 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of at-home photobiomodulation (light therapy) combined with exercise on motor and non-motor symptoms in individuals with moderate Parkinson's disease. Participants will be divided into two groups: one receiving active light therapy and the other receiving a placebo treatment. Each group will consist of 30 participants aged 55-80, and their symptoms will be assessed at the beginning and after four weeks of treatment. The study aims to determine if the combination of light therapy and exercise can significantly improve quality of life and symptom management in Parkinson's patients.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 55-80 with moderate Parkinson's disease who have been participating in an exercise program prior to enrollment.
Not a fit: Patients with severe cognitive impairment, unstable medical conditions, or those who have previously undergone photobiomodulation treatment may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could enhance the management of Parkinson's disease symptoms and improve the quality of life for patients.
How similar studies have performed: Similar approaches using photobiomodulation have shown promise in treating other neurological conditions, suggesting potential for success in this novel application for Parkinson's disease.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Neurologist-diagnosed Hoehn and Yahr Stages 2-3 (moderate) idiopathic PD; * With or without anti-Parkinson's Disease medications; * Able to attend the PD Wellness \& Innovation Centre in Hamilton, Ontario, Canada, * Participating in exercise program prior to enrolment Exclusion Criteria: * Previous PBM treatment * MOCA score of ≤23/30 * Insufficient understanding of English to sign an informed consent, understand teaching and to perform at-home PBM treatment * Physically unable to perform tasks required for outcome measurement testing * History of significant unstable musculoskeletal or neurological disorders or unstable cardiac condition
Where this trial is running
Hamilton, Ontario
- Gaitway Neurophysio and Parkinson's Wellness Innovation Centre — Hamilton, Ontario, Canada (Recruiting)
Study contacts
- Principal investigator: Orla Hares, PT — Neuro Physio at Gaitway Neurophysio and Parkinson's Wellness Innovation Centre
- Study coordinator: Orla Hares, PT
- Email: research@gaitwayneurophysio.com
- Phone: 1-906-974-9892
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.