Lidocaine injections for abdominal wall pain
Official title: Effect of Abdominal Wall Injections on Abdominal Pain
Run by Oregon Health and Science University · NCT06121466 · Data updated 2026-11-12
This will test whether lidocaine injections into the abdominal wall reduce pain in adults with chronic abdominal wall pain.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 100 Years |
| Sex | All |
| Enrollment | 45 (estimated) |
| Sponsor | Oregon Health and Science University Academic / other |
| Locations | 2 sites (Portland, Oregon and 1 other locations) |
| Status | Recruiting |
| Started | January 1, 2023 |
| Main results expected | December 2025 |
| Study ends | December 2025 |
| Registry record updated | September 2, 2025 |
| Trial ID | NCT06121466 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (age ≥18) with localized abdominal wall pain suspected to be from the abdominal wall (positive Carnett's sign or pain near an incision) and average daily pain of at least 3/10 are ideal candidates.
✕Probably not a fit
Patients with suspected visceral causes of pain, an abdominal wall hernia at the pain site, severe lidocaine allergy, prior trigger-point injections for abdominal pain, or inability to complete follow-up are unlikely to benefit from these injections.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective cohort will enroll 30 outpatient adults with chronic abdominal wall pain who receive standard-of-care lidocaine injections at an academic gastroenterology clinic. Baseline evaluation includes medical history, standardized questionnaires (Pain Catastrophizing Scale, Psychological Inflexibility in Pain Scale, PROMIS-29, and a Recurrent Abdominal Pain Intensity and Disability scale) and Quantitative Sensory Testing to measure pain thresholds and tolerance. Pain outcomes are measured at 1, 4, and 12 weeks after injection, with improvement defined as a 50% reduction on an 11-point numeric pain scale. Data analysis will use summary statistics, paired comparisons over time (one-sample t-test or Wilcoxon), chi-square for categorical variables, and logistic regression to identify factors associated with response.
Why it matters
Potential benefit: If successful, this approach could provide meaningful short-term pain relief for some patients with abdominal wall pain and help identify who is most likely to benefit.
How similar studies have gone: Small case series and single-center reports have shown benefit from local anesthetic abdominal wall injections for ACNES and similar syndromes, but high-quality prospective data are still limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Localized abdominal wall pain * Average daily pain (7-day recall) ≥ 3 on a scale of 0-10 * Suspected abdominal wall etiology for abdominal pain * Positive Carnett's sign or pain near an incisional site * 18 years of age or older Exclusion Criteria: * Suspected visceral etiology for the abdominal pain * Severe allergy to lidocaine * Unwillingness or inability to provide informed consent * Low probability of follow-up * Abdominal wall hernia noted at the point of pain * History of trigger point injections for abdominal pain * Bleeding disorder * Pregnancy, incarceration or decisionally impaired
Where it's running
-
Ohsu
Portland, Oregon, United States Recruiting -
Oregon Health Sciences University
Portland, Oregon, United States Recruiting
Study contacts
- Study coordinator: Sophia Lichenstein-Hill, DNP
- Email: lichenst@ohsu.edu
- Phone: 5038801235
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.