Lidocaine infusion to improve recovery after abdominal surgery
Effect of Intraoperative Lidocaine Infusion on Inducing Intestinal Motility and Surgery-induced Release of Pro-inflammatory Cytokines After Abdominal Surgery. A Prospective, Comparative, Randomized Double Blind Controlled Clinical Study
NA · Assiut University · NCT05541640
This study tests if giving lidocaine through an IV can help people recover better and feel less pain after having intestinal surgery.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 60 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Assiut University (other) |
| Locations | 1 site (Assiut) |
| Trial ID | NCT05541640 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of intravenous lidocaine infusion on postoperative recovery in patients undergoing elective intestinal surgery. It compares outcomes between a lidocaine group and a normal saline group to assess the impact on pain management and recovery times. The study aims to evaluate whether lidocaine can reduce the release of pro-inflammatory cytokines and enhance recovery after surgery. The research focuses on patients with a body mass index between 18 and 30 and who are classified as ASA I or II.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older scheduled for elective intestinal surgery with a BMI of 18-30.
Not a fit: Patients with preoperative gastrointestinal dysfunction or a history of long-term opioid use may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to faster recovery and reduced postoperative complications for patients undergoing abdominal surgery.
How similar studies have performed: Previous studies have shown promising results with intravenous lidocaine in enhancing recovery after surgery, indicating that this approach has potential based on earlier findings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age 18 years and older. * Both sexes, males and females * Patients scheduled for elective intestinal surgery. * Body mass index (BMI) 18-30 kg•m-2. * ASA I - II. Exclusion Criteria: * Patient refusal * Patients with preoperative gastrointestinal dysfunction. * Patients with a history of drug abuse, or long-term opioid use. * ASA III and VI * Patients with a history of previous gastrointestinal surgery
Where this trial is running
Assiut
- Assiut university — Assiut, Egypt (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Enhanced Recovery After Surgery