Lidocaine infusion for pain management in spine surgery
The Analgesic Effect of Intravenous Lidocaine Infusion in Combination of Analgesia Nociception Index Monitoring in Spine Surgery.
This study is testing if giving lidocaine during spine surgery can help patients feel less pain and recover better compared to those who only get a saline solution.
Quick facts
| Phase | Phase 4 |
|---|---|
| Study type | Interventional |
| Enrollment | 90 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | Kaohsiung Medical University Chung-Ho Memorial Hospital Academic / other |
| Locations | 1 site (Kaohsiung) |
| Trial ID | NCT05103215 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of continuous lidocaine infusion during elective lumbar spine surgery to enhance recovery after surgery (ERAS). Patients are randomly assigned to receive either lidocaine or saline, with anesthetic drugs adjusted based on specific monitoring parameters. The study aims to assess pain levels, opioid consumption, and recovery quality post-surgery. The goal is to determine if lidocaine can improve outcomes for patients undergoing multiple spine surgeries.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 to 80 with ASA class I-III undergoing elective lumbar spine surgery.
Not a fit: Patients with severe mental disorders, poor liver function, or those currently using opioids may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce postoperative pain and opioid use, leading to faster recovery for patients.
How similar studies have performed: Other studies have shown promising results with lidocaine infusion in surgical settings, suggesting potential for success in this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Twenty to eighty-year-old 2. ASA class I-III patients undergoing 3. Elective lumbar spine surgery under general anesthesia Exclusion Criteria: 1. Unable to understand the Numerical Rating Scale (NRS) 2. Severe mental disorder 3. Poor liver function 4. Pregnant or lactating women 5. Morbidly obese 6. History of epilepsy or allergy to any of the drugs used in this study 7. Current use of opioids 8. Baseline heart rate \<50 beats/min 9. Arrhythmia history with cardiac rhythm device 10. Body weight \<40 kg and \>80kg
Where this trial is running
Kaohsiung
- Kaohsiung Medical University Chung-Ho Memorial Hospital — Kaohsiung, Taiwan (Recruiting)
Study contacts
- Study coordinator: Zhi-Fu Wu, MD
- Email: aneswu@gmail.com
- Phone: 07-3121101
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.