Clinical trial Recruiting at 2 sites Interventional Ages 19 and up

Left versus right nostril for nasotracheal intubation

Official title: The Effect of Nostril Side on Epistaxis During Nasotracheal Intubation

Run by Seoul National University Hospital · NCT06605989 · Data updated 2026-11-12

This test checks whether using the left or right nostril causes more nosebleeds during nasotracheal intubation in adults having elective surgery.

Quick facts

Study typeInterventional
Ages19 Years and up
SexAll
Enrollment208 (estimated)
SponsorSeoul National University Hospital
Academic / other
Locations2 sites (Seoul, Dongjak-gu and 1 other locations)
StatusRecruiting
StartedSeptember 26, 2024
Main results expectedFebruary 28, 2026
Study endsFebruary 28, 2026
Registry record updatedFebruary 11, 2026
Trial IDNCT06605989 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adult patients scheduled for elective surgery who require nasotracheal intubation and do not have severe nasal deformity or active severe epistaxis are ideal candidates.

Probably not a fit

Patients with severe nasal deformity, current severe epistaxis, inability to allow tube insertion in a given nostril, or those undergoing non-elective/emergency intubation are unlikely to benefit from this protocol.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a prospective, randomized controlled comparison of left- versus right-nostril nasotracheal intubation in adult patients undergoing elective surgery. After induction and muscle relaxation, a preformed nasal RAE tube will be inserted 3–4 cm into the assigned nostril and then advanced into the oral cavity, with final nasotracheal intubation performed using Magill forceps. An investigator will inspect the nasal passages with a fiberoptic bronchoscope to record the occurrence and severity of epistaxis. Investigators will compare the incidence and severity of bleeding between the two randomized groups.

Why it matters

Potential benefit: If successful, the result could reduce nosebleeds and related complications by identifying which nostril is safer for nasotracheal intubation.

How similar studies have gone: Previous small trials have compared nostril side and reported mixed results, so the approach is not entirely novel but evidence remains limited.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* adult patients requiring nasotracheal intubation for elective surgery

Exclusion Criteria:

* refuse to participate in the study
* severe deformity in the nose
* current severe epistaxis
* cannot insert the tube into a specific nostril side due to any reason

Where it's running

  • Seoul Metropolitan Government Seoul National University Boramae Medical Center
    Seoul, Dongjak-gu, South Korea
    Recruiting
  • Gangnam Severance Hospital
    Seoul, Gangnam-gu, South Korea
    Recruiting

Study contacts

  • Principal investigator: Jung-Man Lee, M.D.,Ph.D. — Seoul National University College of Medicine, Seoul Metropolitan Government Seoul National University Boramae Medical Center
  • Study coordinator: Jung-Man Lee, M.D., Ph.D.
  • Email: jungman007@gmail.com
  • Phone: +82-2-870-2513

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.