Learning a new walking pattern through exercise after stroke

Feedback and Cognition During Locomotor Learning Post Stroke

NA · University of Delaware · NCT03726047

This study is testing if adding a short exercise session after learning a new walking pattern can help stroke survivors remember how to walk better both right away and the next day.

Quick facts

PhaseNA
Study typeInterventional
Enrollment80 (estimated)
Ages18 Years to 85 Years
SexAll
SponsorUniversity of Delaware (other)
Locations1 site (Newark, Delaware)
Trial IDNCT03726047 on ClinicalTrials.gov

What this trial studies

This study focuses on individuals with chronic stroke who will learn a new walking pattern using distorted visual feedback. Participants will be randomly assigned to either a control group, which will perform the learning task alone, or an exercise group, which will engage in 5 minutes of exercise after the initial retention test. The goal is to assess how exercise influences the retention of the learned walking pattern both immediately and 24 hours later. By personalizing rehabilitation based on individual factors, the study aims to enhance motor learning and improve walking capacity in stroke survivors.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18-85 who have experienced a single, unilateral stroke more than six months ago and can walk independently.

Not a fit: Patients with cerebellar strokes, other neurological conditions, or those unable to walk prior to their stroke may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve walking rehabilitation outcomes for stroke survivors.

How similar studies have performed: While the specific approach of combining exercise with motor learning is innovative, similar studies have shown promise in enhancing rehabilitation outcomes for stroke patients.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age 18-85 Single, unilateral, chronic stroke (\>6 months post-stroke), confirmed by MRI or CT scan Score \>1 on question 1b and \>0 on question 1c of the NIH Stroke Scale Able to walk at self-selected speed without assistance from another person Resting heart rate between 40-100 beats per minute Resting blood pressure between 90/60 to 185/100

Exclusion Criteria:

Evidence of cerebellar stroke on clinical MRI or CT scan, because of role of cerebellum in learning Other neurologic conditions in addition to stroke Inability to walk outside the home prior to the stroke Coronary artery bypass graft or myocardial infarction within past 3 months, Musculoskeletal pain that limits walking Inability to communicate with investigators Visual field cut Neglect Unexplained dizziness in last 6 months

Where this trial is running

Newark, Delaware

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stroke

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.