Clinical trial Recruiting at 1 site Interventional Ages 18 to 85

Learning a new walking pattern through exercise after stroke

Official title: Feedback and Cognition During Locomotor Learning Post Stroke

Run by University of Delaware · NCT03726047 · Data updated 2026-11-12

This study is testing if adding a short exercise session after learning a new walking pattern can help stroke survivors remember how to walk better both right away and the next day.

Quick facts

Study typeInterventional
Ages18 Years to 85 Years
SexAll
Enrollment80 (estimated)
SponsorUniversity of Delaware
Academic / other
Locations1 site (Newark, Delaware)
StatusRecruiting
StartedDecember 1, 2019
Main results expectedJanuary 31, 2027
Study endsFebruary 2027
Registry record updatedMay 20, 2026
Trial IDNCT03726047 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are adults aged 18-85 who have experienced a single, unilateral stroke more than six months ago and can walk independently.

Probably not a fit

Patients with cerebellar strokes, other neurological conditions, or those unable to walk prior to their stroke may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on individuals with chronic stroke who will learn a new walking pattern using distorted visual feedback. Participants will be randomly assigned to either a control group, which will perform the learning task alone, or an exercise group, which will engage in 5 minutes of exercise after the initial retention test. The goal is to assess how exercise influences the retention of the learned walking pattern both immediately and 24 hours later. By personalizing rehabilitation based on individual factors, the study aims to enhance motor learning and improve walking capacity in stroke survivors.

Why it matters

Potential benefit: If successful, this approach could significantly improve walking rehabilitation outcomes for stroke survivors.

How similar studies have gone: While the specific approach of combining exercise with motor learning is innovative, similar studies have shown promise in enhancing rehabilitation outcomes for stroke patients.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

Age 18-85 Single, unilateral, chronic stroke (\>6 months post-stroke), confirmed by MRI or CT scan Score \>1 on question 1b and \>0 on question 1c of the NIH Stroke Scale Able to walk at self-selected speed without assistance from another person Resting heart rate between 40-100 beats per minute Resting blood pressure between 90/60 to 185/100

Exclusion Criteria:

Evidence of cerebellar stroke on clinical MRI or CT scan, because of role of cerebellum in learning Other neurologic conditions in addition to stroke Inability to walk outside the home prior to the stroke Coronary artery bypass graft or myocardial infarction within past 3 months, Musculoskeletal pain that limits walking Inability to communicate with investigators Visual field cut Neglect Unexplained dizziness in last 6 months

Where it's running

  • University of Delaware
    Newark, Delaware, United States
    Recruiting

Study contacts

  • Principal investigator: Darcy Reisman, PhD — University of Delaware
  • Study coordinator: Darcy Reisman, PhD
  • Email: dreisman@udel.edu
  • Phone: 3028310508

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.