Laser versus crystallized phenol for pilonidal sinus in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is a single-center, randomized study comparing laser ablation to crystallized phenol for adults with primary uncomplicated sacrococcygeal pilonidal sinus disease. Seventy-two? Wait: the protocol plans 120 participants, 60 per arm, randomized 1:1 with allocation concealment. All participants undergo a ~1 cm incision, cleaning of the sinus, and curettage, followed by either laser treatment or phenol application, with possible repeat sessions during healing. The primary endpoint is pain on postoperative day 1, measured by a visual analog scale; key secondary endpoints include 30-day epithelialization, time to epithelialization, day-7 pain, analgesic use duration, return to daily activities/work, early local complications, and 6-month recurrence. Outcomes will inform relative short-term pain and healing trajectories between the two minimally invasive options.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 18 years or older
* Diagnosis of primary chronic sacrococcygeal pilonidal sinus disease
* Uncomplicated disease
* Suitability for minimally invasive treatment
* Provision of written informed consent

Exclusion Criteria:

* Acute pilonidal abscess
* History of pilonidal abscess drainage
* Previous surgical or interventional treatment for pilonidal sinus disease
* Recurrent pilonidal disease
* Complex pilonidal disease or marked lateral extension
* Immunosuppression, chronic steroid use, or systemic conditions that may significantly impair wound healing
* Inability to attend regular follow-up
* Refusal to participate in the study

Where it's running

• Sanliurfa Education and Research Hospital
  Sanliurfa, Şanlıurfa, Turkey (Türkiye) Recruiting

Study contacts

• Study coordinator: Vedat Kaplan
• Email: vedat_kaplan_@hotmail.com
• Phone: +905459045165

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Pilonidal sinus care with VAAPS and loose seton drainage after VAAPS

  This study tests whether adding a loose glove-edge seton drainage to VAAPS can allow patients to manage wound care at home without daily flushing.

  Recruiting Peking University People's Hospital · Beijing, Beijing Municipality · NCT07855107

• Comparing two local anesthesia methods for pain after laser treatment of pilonidal sinus

  This study will see if standard lidocaine injections or tumescent local anesthesia causes less postoperative pain for people having laser treatment for pilonidal sinus disease.

  Recruiting Opća županijska bolnica Požega · Požega · NCT07408414

• Adding phenol to laser treatment for pilonidal sinus healing

  This will see if adding crystallized phenol to a day-surgery laser treatment helps adults with primary pilonidal sinus heal faster and return to normal activities sooner.

  Recruiting Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital · Istanbul, Other · NCT07023952

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.