Laser versus conventional pulpotomy for mature molars with irreversible pulpitis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Sixty restorable permanent molars with symptomatic irreversible pulpitis will be randomized into three groups receiving photobiomodulation pulpotomy, photocoagulation pulpotomy, or conventional pulpotomy, and all teeth will be capped with bioceramic putty. Postoperative pain will be recorded at 24, 48 and 72 hours and at one week using a numerical rating scale, and clinical plus periapical radiographic assessments will occur at 1, 3, 6 and 12 months. Cone-beam CT scans will be taken immediately after treatment and at the end of follow-up to evaluate dentin bridge formation, and automated segmentation using artificial intelligence will quantify changes in radicular pulp volume. The trial compares clinical pain, radiographic healing, and CBCT-derived pulp metrics to determine whether laser methods offer improved outcomes over conventional pulpotomy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Permanent molar teeth with symptomatic irreversible pulpitis.
* The patient should be ≥ 16 to 50 years old.
* Teeth should give positive response to cold testing and clinical diagnosis of SIP with or without periapical rarefaction.
* Teeth will be selected only if they are restorable.
* Patient medically healthy and free from systemic diseases. ASA I, II.
* patients who agreed to participate in the study to attend the control visits.
* Teeth with periapical index score (PAI) 1 and 2 will be selected

Exclusion Criteria:

* Teeth with necrotic pulp, resorption or subgingival caries.
* Teeth with open apices.
* Medically compromised patients.
* Pregnant patients.
* Patients with uncontrollable bleeding from the radicular pulp.
* Patients with (PAI) score 3-5 will be excluded from the study

Where it's running

• Faculty of Dentistry
  Alexandria, Egypt Recruiting

Study contacts

• Principal investigator: Rania Noaman ELbackly, Professor — Endodontics, Conservative Dentistry Department, Faculty of Dentistry, Alexandria University, Alexandria, Egypt. Tissue Engineering Laboratories, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.
• Study coordinator: Rana Mahmoud Hegazi, Assistant lecturer
• Email: ranahegazi1991@gmail.com
• Phone: 01094428209

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.