Laser speckle imaging to monitor leg perfusion before, during and after revascularization

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study will use laser speckle contrast imaging (LSCI) to record real-time perfusion of the lower limb before, during, and after revascularization procedures. LSCI measurements will be performed perioperatively and compared with standard indocyanine green near-infrared fluorescence (ICG NIRF) and temperature readings to explore correlations. Participants are patients scheduled for lower-extremity revascularization at Leiden University Medical Center who undergo pre- and postoperative ICG NIRF imaging. The study aims to test feasibility and signal quality of LSCI as a quick, dye-free alternative for bedside perfusion monitoring.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Scheduled for lower-extremity revascularization
* Undergoing pre- and postoperative indocyanine near-infrared fluorescence perfusion measurements

Exclusion Criteria:

Any condition that the investigator considers to be potentially jeopardizing the patient's wellbeing or the study objectives

Where it's running

• Leiden University Medical Center
  Leiden, South Holland, Netherlands Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.