L-PRF versus sticky tooth versus sticky bone to fill the shield-implant gap during AI-guided socket-shield immediate front-tooth implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Adults with one non-restorable anterior tooth and sufficient apical/palatal bone will receive socket-shield immediate implant placement using an AI-assisted, patient-specific guide created from intraoral scan and CBCT superimposition. The shield-implant 'jumping gap' will be filled with one of three modalities: L-PRF alone, sticky tooth (autogenous dentin + i-PRF), or sticky bone (particulate graft + i-PRF). CBCT imaging will be obtained immediately, at three months, and at six months to quantify hard- and soft-tissue dimensional changes. The investigators hypothesize that cohesive biologic composites (sticky tooth and sticky bone) will provide superior space maintenance and early wound stability compared with PRF alone.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Medically healthy patients according to the American Society of Anesthesiologists (ASA) physical status classification system; only patients belonging to ASA I and ASA II categories will be included in this study.
* Age \> 18 years.
* Patients presenting with one non-restorable hopeless anterior tooth due to extensive caries, cervical/root fracture, vertical or oblique root fracture, multiple failed endodontic treatments, or root resorption.
* Sufficient apical/palatal bone to obtain primary implant stability.

Exclusion Criteria:

* Patients belonging to ASA III, ASA IV and ASA V will be excluded.
* Vertical root fracture involving the labial aspect of the root planned to be retained as the facial shield.
* Horizontal root fracture that is too far apically located.
* Presence of acute (active) periapical infection.
* Large chronic periapical lesion.
* Lack of sufficient bone apical to the extraction socket to obtain primary stability. \* Ankylosed tooth positioned too apically in relation to adjacent teeth.

Where it's running

• faculty of dentistry, kafrelsheikh University
  Kafr ash Shaykh, Kafrelsheikh, Egypt Recruiting
• Walid Elamrousy
  Kafr ash Shaykh, Egypt Recruiting

Study contacts

• Study coordinator: Walid Elamrousy, PhD
• Email: waled_hammed@den.kfs.edu.eg
• Phone: +201029552024

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.