L-PRF versus connective tissue graft with a customized healing abutment for immediate single-tooth implants

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional comparison enrolls patients receiving immediate implants for non-restorable single-rooted maxillary centrals, canines, or premolars and treats the site with either L-PRF or an autologous connective tissue graft plus a customized healing abutment. Participants must have an intact labial/buccal bone plate, sufficient bone volume and width confirmed by CBCT, good oral hygiene, and be nonsmokers. Soft-tissue and hard-tissue outcomes such as gingival recession, soft-tissue thickness, and peri-implant bone levels will be recorded over follow-up visits using clinical measurements and imaging. The protocol excludes patients with insufficient bone, active infection, systemic diseases, pregnancy, or current cancer therapy.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Intact labial/buccal bone plate
* The presence of non-restorable single-rooted maxillary centrals, canines or premolars.
* Sufficient bone volume.
* Good oral hygiene.
* Nonsmokers.
* Sufficient bone width (≥ 1 mm) in the buccal plate of the remaining bone to place an implant confirmed by cone beam computer tomography (CBCT).

Exclusion Criteria:

* Insufficient bone volume.
* Active infection.
* Patients on chemotherapy or radiotherapy.
* Patients who have systemic disorders {uncontrolled diabetes mellitus, autoimmune disease, …etc},
* Pregnant patients,
* Patients with bone diseases
* Presence of periapical pathology.

Where it's running

• Kafrelsheikh University
  Kafr ash Shaykh, Kafrelsheikh, Egypt Recruiting

Study contacts

• Study coordinator: Ahmed Atef Salem, General doctor
• Email: dent.ahmedatef@gmail.com
• Phone: 0201007737797

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.