L-carnitine for preterm babies with respiratory distress syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study enrolls preterm neonates with respiratory distress syndrome who are admitted to the NICU within 24 hours of birth. Participants receive L-carnitine supplementation in addition to standard neonatal care and are compared with infants receiving standard care alone. Primary short-term outcomes include weight gain, hospital discharge rate, and early mortality, while safety and metabolic measures will also be monitored. Neonates with gastrointestinal anomalies, confirmed or suspected sepsis at enrollment, or an expected survival under 48 hours are excluded, and the trial is conducted at a single center in Muzaffargarh, Pakistan.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Preterm neonates
* Either gender
* With RDS
* Admitted to the neonatal intensive care unit (NICU) within 24 hours of birth .

Exclusion Criteria:

* Neonates with gastrointestinal tract (GIT) anomalies
* With confirmed or suspected sepsis at the time of enrollment
* Neonates whose clinical condition contraindicates study participation (e.g., expected survival \<48 hours, as judged by the neonatologist).

Where it's running

• Recep Tayyip Erdogan Hospital/Indus Hospital & Health Network
  Muzaffargarh, Punjab Province, Pakistan Recruiting

Study contacts

• Principal investigator: Muhammad Sarfraz, FCPS — Recep Tayyip Erdogan Hospital, Muzaffargarh
• Study coordinator: Muhammad Sarfraz, FCPS
• Email: drfraz1986@gmail.com
• Phone: +923336464238

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.