Krill oil to improve muscle strength in adults with long-term health conditions

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, double-blind 12-week pilot trial will enroll 30 adults who will receive either 4 g/day krill oil (Superba™) or 4 g/day placebo vegetable oil. Participants will be asked to maintain their usual diet and activity while researchers measure grip strength and collect dietary and activity data using the EPIC FFQ and IPAQ, plus a weekly fish consumption log. Eligibility excludes people with cancer, neurocognitive disorders, certain cardiovascular risks (for example aortic stenosis or prior haemorrhagic stroke), current anticoagulant therapy, pregnancy or breastfeeding, fish allergy, or regular oily fish or fish oil use. The pilot will test feasibility and provide initial effect-size data to inform a larger trial.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Men and women aged ≥18 years who are in the high-risk long-term condition group (having one or more LTCs, including rheumatoid arthritis, gout, type 2 diabetes, coronary heart disease, and stroke \[including transient ischemic attack, TIA\]).

Exclusion Criteria:

* Participants are diagnosed with and being treated for any type of cancer.
* Presence of neurocognitive disorders or any health condition affecting memory (e.g., Alzheimer's disease, dementia).
* Aortic stenosis, history of haemorrhagic stroke, or presence of aneurysms.
* Current anticoagulant therapy.
* Use of any muscle mass supplements or presence of physiological conditions such as pregnancy or breastfeeding.
* History of allergy to fish or fish oil.
* Regular consumption of more than one portion of oily fish per week, or use of fish oil or krill oil supplements.

Where it's running

• Lab 242, Sir James Black Building, University of Glasgow
  Glasgow, Lanarkshire, United Kingdom Recruiting
• University of Glasgow
  Glasgow, Lanarkshire, United Kingdom Not yet recruiting

Study contacts

• Study coordinator: Professor Stuart Gray
• Email: stuart.gray@glasgow.ac.uk
• Phone: +441413302569

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.