Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Knee MRI as it bends: a first look at how the knee moves from straight to bent

Official title: MRI Assessment of Knee Kinematics From Extension to Flexion - Exploratory Study

Run by GCS Ramsay Santé pour l'Enseignement et la Recherche · NCT07016906 · Data updated 2026-11-12

This study tests knee MRI at different bending angles in healthy adults to see how the knee’s bones slide and roll when the leg flexes.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment36 (estimated)
SponsorGCS Ramsay Santé pour l'Enseignement et la Recherche
Academic / other
Locations1 site (Marcy-l'Étoile)
StatusRecruiting
StartedJuly 8, 2025
Main results expectedSeptember 30, 2026
Study endsSeptember 30, 2026
Registry record updatedAugust 20, 2026
Trial IDNCT07016906 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Healthy adults aged 18–40 without knee injury or surgery.

Probably not a fit

Individuals with knee disease, prior knee surgery, obesity (BMI >30), or contraindications to MRI may not benefit.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Healthy volunteers aged 18–40 will undergo MRI scans of the knee at various degrees of flexion to observe sliding and roll-back motion of the knee joints. The study aims to overcome technical limits of standard MRI coils by using specialized positioning to capture knee movement beyond 30 degrees of flexion. Researchers will analyze how the tibia rotates internally and how the knee surfaces translate relative to the femur during flexion. The findings could improve understanding of knee kinematics and help future imaging approaches. This is an exploratory, interventional imaging study with no therapeutic intervention.

Why it matters

Potential benefit: If successful, the study could improve MRI methods for studying knee motion and contribute to better diagnostic imaging of knee kinematics.

How similar studies have gone: Previous MRI work has explored knee motion, but this study uses specialized positioning to enable extended flexion imaging, making it relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy volunteers (no damage to either knee)
* Male or female, aged between 18 and 40
* Healthy volunteer affiliated to or benefiting from a social security scheme
* A healthy French-speaking volunteer who has signed an informed consent form.

Exclusion Criteria:

* Contraindication to MRI
* Joint osteoarthritis
* BMI \> 30
* Previous trauma or surgery to the knee
* Recurrence of sprains
* Knee trauma other than sprain
* Protected person: adult under guardianship, curatorship or other legal protection, deprived of liberty by judicial or administrative decision.
* Pregnant or breast-feeding woman

Where it's running

  • Hawkcell
    Marcy-l'Étoile, France
    Recruiting

Study contacts

Similar studies

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.