Kaempferol facial masks to improve skin biophysical properties
Official title: Clinical Evaluation of the Skincare Benefits of Kaempferol-Containing Masks
Run by Kaohsiung Medical University Chung-Ho Memorial Hospital · NCT07458334 · Data updated 2026-11-12
We will test whether Kaempferol-containing facial masks improve skin biophysical properties in women aged 25–60 compared with hyaluronic acid masks.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 25 Years to 60 Years |
| Sex | Women only |
| Enrollment | 60 (estimated) |
| Sponsor | Kaohsiung Medical University Chung-Ho Memorial Hospital Academic / other |
| Locations | 1 site (Kaohsiung City) |
| Status | Recruiting |
| Started | February 9, 2026 |
| Main results expected | December 2026 |
| Study ends | March 2027 |
| Registry record updated | March 9, 2026 |
| Trial ID | NCT07458334 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Women aged 25–60 who are not pregnant or breastfeeding, do not have active inflammatory skin disease or severe systemic illness, and are not allergic to the product are ideal candidates.
✕Probably not a fit
People who are pregnant or breastfeeding, have psoriasis, atopic dermatitis, active skin infections, severe systemic diseases, known allergy to the product, men, or those outside the 25–60 age range are unlikely to benefit or are excluded from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This open-label, two-arm trial in Kaohsiung will compare a Kaempferol-containing facial mask to a hyaluronic acid-containing facial mask in female participants aged 25–60. Enrolled participants will receive one of the two masks and undergo objective measurements of skin biophysical properties at baseline and after the treatment period. Key exclusions include pregnancy or breastfeeding, psoriasis or atopic dermatitis, recent systemic corticosteroid or oral retinoid use, severe systemic illness, infectious diseases, psychiatric disorders, external skin trauma or infections, and allergy to the product. The primary focus is on short-term cosmetic and biophysical skin endpoints rather than long-term clinical outcomes.
Why it matters
Potential benefit: If successful, Kaempferol masks could provide improved skin hydration, elasticity, or barrier function as a topical cosmetic option.
How similar studies have gone: Topical antioxidants and hyaluronic-acid products have shown cosmetic benefits in prior studies, but clinical evidence specifically for Kaempferol-containing masks in humans is limited.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Female subjects between 25 and 60 years old Exclusion Criteria: * Pregnant or breastfeeding women * Subjects who are allergic to the product * Subjects with psoriasis or atopic dermatitis * Subjects who have taken systemic corticosteroids within 2 weeks * Subjects who have taken oral retinoid within 1 week * Subjects with severe medical conditions, such as cardiovascular, liver, kidney, or hematopoietic system disorders * Subjects with tuberculosis * Subjects with viral hepatitis or other infectious diseases * Subjects with psychiatric disorders * Subjects with external trauma or infections
Where it's running
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Kaohsiung Medical University Chung-Ho Memorial Hospital
Kaohsiung City, Taiwan Recruiting
Study contacts
- Study coordinator: Stephen Chu-Sung Hu
- Email: stephen@kmu.edu.tw
- Phone: +886-7-3121101
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.