IVF outcomes for women with Polycystic Ovary Syndrome
IVF\ICSI Outcome in Women With Polycystic Ovary Syndrome Compared With Non Polycystic Ovary Syndrome Women
This study looks at how well IVF and ICSI work for women with Polycystic Ovary Syndrome who are having trouble getting pregnant.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 156 (estimated) |
| Ages | 20 Years to 35 Years |
| Sex | Female |
| Sponsor | Egymedicalpedia Industry-sponsored |
| Locations | 1 site (Asyut) |
| Trial ID | NCT05756023 on ClinicalTrials.gov |
What this trial studies
This study investigates the outcomes of in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in women diagnosed with Polycystic Ovary Syndrome (PCOS). It focuses on sub-fertile women who may require assisted reproductive techniques due to challenges such as anovulation and hormonal imbalances. The study aims to evaluate the pregnancy rates associated with these reproductive techniques while considering the unique challenges faced by women with PCOS, including potential complications and the impact of obesity on fertility outcomes.
Who should consider this trial
Good fit: Ideal candidates for this study are women of reproductive age diagnosed with PCOS who experience oligo-ovulation or anovulation.
Not a fit: Patients with androgen-secreting tumors, major uterine anomalies, or other significant endocrine disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could improve IVF success rates for women with PCOS, leading to higher pregnancy and live birth rates.
How similar studies have performed: Other studies have explored IVF outcomes in PCOS patients, but this specific approach to modifying standard protocols is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Oligo-ovulation or anovulation. * Clinical and/or biochemical hyper androgenesim. * Polycystic ovaries. Exclusion Criteria: 1. Androgen-secreting tumors (ovarian or adrenal). 2. Adult-onset congenital adrenal hyperplasia. 3. Thyroid diseases. 4. Cushing's syndrome. 5. Diabetes Mellitus. 6. recurrent ICSI failure 7. endocrine, hematologic and autoimmune disorders 8. Non chromosomal and genetic abnormalities 9. Major uterine anomalies, bad surgical history, sever endometriosis, , hydrosalpinx, uterine fibroids 10. Azospermia
Where this trial is running
Asyut
- Assuit University hospitals — Asyut, Egypt (Recruiting)
Study contacts
- Study coordinator: Islam Mahfouz, MSC
- Email: islam.ibrahim@med.aun.edu.eg
- Phone: 01118434861
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.