IVF outcomes for women with Polycystic Ovary Syndrome

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the outcomes of in-vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) in women diagnosed with Polycystic Ovary Syndrome (PCOS). It focuses on sub-fertile women who may require assisted reproductive techniques due to challenges such as anovulation and hormonal imbalances. The study aims to evaluate the pregnancy rates associated with these reproductive techniques while considering the unique challenges faced by women with PCOS, including potential complications and the impact of obesity on fertility outcomes.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Oligo-ovulation or anovulation.
* Clinical and/or biochemical hyper androgenesim.
* Polycystic ovaries.

Exclusion Criteria:

1. Androgen-secreting tumors (ovarian or adrenal).
2. Adult-onset congenital adrenal hyperplasia.
3. Thyroid diseases.
4. Cushing's syndrome.
5. Diabetes Mellitus.
6. recurrent ICSI failure
7. endocrine, hematologic and autoimmune disorders
8. Non chromosomal and genetic abnormalities
9. Major uterine anomalies, bad surgical history, sever endometriosis, , hydrosalpinx, uterine fibroids
10. Azospermia

Where it's running

• Assuit University hospitals
  Asyut, Egypt Recruiting

Study contacts

• Study coordinator: Islam Mahfouz, MSC
• Email: islam.ibrahim@med.aun.edu.eg
• Phone: 01118434861

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Adding quercetin or alpha-lipoic acid to metformin for women with PCOS

  This trial will see if adding quercetin or alpha-lipoic acid to metformin improves hormones, blood sugar, cholesterol, and quality of life in women aged 18–40 with PCOS.

  Recruiting Phase 2 Al-Mustansiriyah University · Baghdad, Karkh · NCT07182526

• Comparing letrozole alone versus letrozole with levothyroxine for women with PCOS and subclinical hypothyroidism

  This study is testing if adding levothyroxine to letrozole helps women with PCOS and low thyroid function get pregnant more effectively than letrozole alone.

  Recruiting Al-Azhar University · Cairo · NCT06041204

• Using Semaglutide to Restore Ovulation in Young Women with PCOS

  This study is testing if a medication called semaglutide can help young women with PCOS and obesity start ovulating again.

  Recruiting Phase 3 University of Colorado, Denver · Aurora, Colorado · NCT05819853

• Using LC-MS/MS to profile androgens for PCOS diagnosis

  This study tests whether LC-MS/MS measurement of androgen profiles can help diagnose PCOS in women compared with healthy controls.

  Recruiting Women's Hospital School Of Medicine Zhejiang University · Hangzhou, Zhejiang · NCT07916909

• Brown adipose tissue responses in PCOS with infrared thermography and inositol

  This study tests whether brown fat activity, measured by infrared skin temperature and UCP-1 levels, differs among women with PCOS (normal weight or overweight/obese) and healthy controls, and whether 12 weeks of inositol changes those responses in overweight/obese PCOS participants.

  Recruiting at 2 sites Istanbul Health and Technology University · Istanbul and 1 other locations · NCT07896642

• Risk tool for blood-clotting problems in adolescents and women with PCOS

  This project will try to build a risk model to spot decreased protein C or S and other clotting abnormalities in females aged 14–45 who have PCOS.

  Recruiting Guangdong Women and Children Hospital · Guangzhou, Guangdong · NCT07571096

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.