IVC collapsibility monitoring during lumbar stabilization surgery
Hemodynamic Assessment Using the Inferior Vena Cava Collapsibility Index in Patients Undergoing Lumbar Stabilization Surgery
This study will see if ultrasound measurements of the inferior vena cava (IVC) collapsibility can show changes in fluid status during lumbar spine stabilization surgery in adults.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 128 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Trabzon Kanuni Education and Research Hospital Academic / other |
| Locations | 2 sites (Trabzon and 1 other locations) |
| Trial ID | NCT07549165 on ClinicalTrials.gov |
What this trial studies
This prospective observational study uses bedside ultrasonography to measure IVC diameter and calculate the IVC collapsibility index at predefined perioperative time points in adults having elective lumbar stabilization under general anesthesia in the prone position. Measurements will be taken preoperatively, after induction of anesthesia, and before extubation, with additional intraoperative timing as feasible. Routine hemodynamic data such as blood pressure and heart rate will be recorded in parallel. The IVC diameter and collapsibility index will be analyzed to track intravascular volume changes across the perioperative period.
Who should consider this trial
Good fit: Adults (≥18 years) with ASA physical status I–III scheduled for elective lumbar stabilization under general anesthesia who can obtain adequate IVC ultrasound images and have BMI ≤30 kg/m².
Not a fit: Patients with ASA IV, severe heart failure (EF <40%), pulmonary hypertension (PAP >40 mmHg), obesity (BMI >30 kg/m²), intra-abdominal pathology or ascites, pregnancy, emergency or revision surgery, or inability to obtain adequate IVC imaging are unlikely to benefit.
Why it matters
Potential benefit: If successful, IVC collapsibility could provide a simple, non-invasive bedside tool to monitor intravascular volume and help guide fluid management during lumbar spine surgery.
How similar studies have performed: Previous studies have shown IVC collapsibility can correlate with intravascular volume in some settings, but its accuracy and reliability during prone lumbar spine surgery under general anesthesia are not well established.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥ 18 years * Patients classified as ASA physical status I-II-III * Patients scheduled for elective lumbar spine stabilization surgery under general anesthesia * Ability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging * Provision of written informed consent Exclusion Criteria: * Age younger than 18 years * Emergency surgery * American Society of Anesthesiologists (ASA) physical status IV * Patients undergoing revision lumbar stabilization surgery * Baseline systolic blood pressure \>180 mmHg or \<90 mmHg * Heart failure with ejection fraction (EF) \<40% * Pulmonary artery pressure (PAP) \>40 mmHg * Presence of intra-abdominal mass, ascites, or increased intra-abdominal pressure * Body mass index (BMI) \>30 kg/m² * Pregnancy * Patients with neurological or psychiatric disorders * Inability to obtain adequate inferior vena cava (IVC) ultrasonographic imaging * Refusal to provide written informed consent
Where this trial is running
Trabzon and 1 other locations
- Trabzon University Faculty of Medicine Kanunı Training and Research Hospital ,Trabzon — Trabzon, Turkey (Türkiye) (Recruiting)
- Trabzon University Faculty of Medicine, Kanuni Training and Research Hospital — Trabzon, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Şeyma Yüksel Ayar, MD
- Email: balseymayuksel@hotmail.com
- Phone: +905395655853
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.