Isometric wall squat exercise to lower blood pressure in adults with hypertension

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized controlled trial assigns about 100 adults with essential hypertension to either a home-based isometric wall squat program or standard hypertension care for 12 weeks. The IWS group performs four sets of up to 2 minutes, three times per week, with intensity tailored from a baseline test. Blood pressure will be continuously monitored over 24 hours at baseline and after 12 weeks using a ring-type device to assess changes in mean systolic pressure, diastolic pressure, variability, and patterns across day and night. Secondary outcomes include office blood pressure, physical function, quality of life, exercise self-efficacy, and adherence. The study is single-center, conducted at Korea University Guro Hospital, and will help determine if this simple home exercise could augment blood pressure control beyond standard care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Adult men and women aged 19 years or older
2. Patients diagnosed with essential hypertension and undergoing outpatient follow-up
3. Subjects whose antihypertensive medication has been stably maintained for at least 4 weeks prior to enrollment
4. Clinic blood pressure of systolic blood pressure (SBP) ≥130 mmHg or diastolic blood pressure (DBP) ≥80 mmHg.
5. Participants who are able to perform wall squats and who have provided written informed consent after receiving an explanation of the study and reviewing the informed consent form

Exclusion Criteria:

1. Participants with unstable angina or a diagnosis of myocardial infarction or stroke within the past 6 months.
2. Participants diagnosed with New York Heart Association (NYHA) functional class III-IV heart failure, severe valvular heart disease, or severe arrhythmia.
3. Participants with severe knee, hip, or spinal disorders that prevent them from performing wall squats.
4. Participants with severe renal or hepatic disease or severe cognitive impairment.
5. Participants who are currently pregnant or have the potential to become pregnant.
6. Participants aged 65 years or older who have a score of 3-5 (frail) on the K-FRAIL scale. However, such participants may be allowed to participate on an individual basis, following consultation with the Principal Investigator, if the treating physician clinically determines that the intervention can be performed safely.

Where it's running

• Korea University Guro Hospital
  Seoul, Seoul, South Korea Recruiting

Study contacts

• Principal investigator: Jin-Oh Na, MD, PhD — Korea University Guro Hospital
• Study coordinator: Jin-Oh Na, MD, PhD
• Email: koolup93@gmail.com
• Phone: 82-2-2626-3025

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.