Isokinetic strength training for patients with one-sided weakness after stroke

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effects of isokinetic strength training on knee flexor and extensor muscles in hemiparetic patients who exhibit knee extension thrust during walking. It employs a single case experimental design with multiple baseline assessments, allowing for the measurement of intervention effects on walking performance. Patients will undergo a conventional rehabilitation program before the introduction of isokinetic training, which will be randomized to start after a baseline period of 3 to 5 weeks. A total of 12 patients will be included, divided equally between those in the subacute and chronic stages of stroke.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Hemiparetic patient (hemorragic or ischemic stroke)
* Subacute stage (\< 6 Months) ou chronic stage of stroke (\> 6 months) (6 patients in each group)
* Age between 18 and 75 years
* Able to walk 10 meters independently without any assistive devices
* Knee extension thrust during stance phase of gait cycle (rapid posterior movement of the knee toward extension)
* Scheduled rehabilitation program with isokinetic strength training
* affiliation to a social security
* Patients who received and signed informed consent

Exclusion Criteria:

* Major comprehension deficit that not allow to give informed consent and participate to isokinetic strength training (assessed with comprehension subscore of Langague screening Test)
* non stable (unstable cardiovascular condition)
* musculoskeletal disorders with knee pain that not allowed isokinetic strength training
* Botulinum toxin injection less than 3 months or repeated injection in lower limb,
* Proprioception trouble assessed with proprioception section of the Fugl-Meyer Assessment \[FMA-P\] 0/2
* spasticity of triceps surae ≥2 (Modified Ashworth scale)
* ankle dorsiflexion angle less than 90°
* pregnant women or breastfeeding
* persons with safety measure

Where it's running

• CHU de Rennes
  Rennes, France Recruiting

Study contacts

• Principal investigator: Sophie HAMEAU, PhD — Rennes University Hospital
• Study coordinator: Sophie HAMEAU, PhD
• Email: sophie.hameau@chu-rennes.fr
• Phone: 299284218

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.