Isokinetic knee exercises to improve proprioception after stroke
Evaluation of the Effect of Knee Isokinetic Strengthening Exercises on Proprioception and Balance in Stroke Patients
This will test whether isokinetic knee-strengthening exercises help people 3-12 months after a stroke regain movement sense and balance.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 34 (estimated) |
| Ages | 35 Years to 75 Years |
| Sex | All |
| Sponsor | Ankara Etlik City Hospital Government |
| Locations | 1 site (Ankara, Yenimahalle) |
| Trial ID | NCT07106619 on ClinicalTrials.gov |
What this trial studies
This interventional program enrolls people 3-12 months after a stroke to compare knee isokinetic muscle-strengthening exercises with a conventional rehabilitation program. Participants perform targeted, controlled knee strengthening on an isokinetic dynamometer alongside standard therapy over a defined treatment period. Outcomes include measures of proprioception, balance, and lower-extremity strength taken before and after the intervention. The approach aims to determine if adding isokinetic training yields greater sensory and functional gains than usual care.
Who should consider this trial
Good fit: Ideal candidates are people aged 35-75 who are 3-12 months post-stroke with at least grade 3 manual muscle strength in ankle dorsiflexion and knee extension, normal passive joint range of motion, and a Mini-Mental State Exam score above 23.
Not a fit: Patients with significant spasticity (modified Ashworth scale >1+), other neurologic or orthopedic conditions affecting the legs, diabetic polyneuropathy, prior stroke, or poor general health are unlikely to benefit from this protocol.
Why it matters
Potential benefit: If successful, participants could gain improved proprioception, stronger lower limbs, and better balance, which may reduce disability and fall risk after stroke.
How similar studies have performed: Previous research supports that targeted sensory and strength training can improve proprioception and balance after stroke, but studies specifically using isokinetic protocols are limited.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * At least 3 months and no more than 1 year must have passed since the date of the incident * Be between 35 and 75 years of age * Manual muscle testing of the affected lower extremity shows at least 3 in ankle dorsiflexion and knee extension * No limitation in passive joint range of motion in the lower extremity * Mini mental test score \> 23 Exclusion Criteria: * Presence of spasticity according to the modified Ashworth scale \> 1+ * Presence of neurological disease other than stroke * Presence of other medical conditions that may cause sensorimotor dysfunction in the lower extremities (e.g., diabetic polyneuropathy) * Presence of orthopaedic problems affecting lower extremity function * Previous history of stroke or ischaemic attack * Poor general health status (e.g. severe heart failure, COPD)
Where this trial is running
Ankara, Yenimahalle
- Ankara Etlik City Hospital — Ankara, Yenimahalle, Turkey (Türkiye) (Recruiting)
Study contacts
- Study coordinator: Ayşe Naz Kalem Özgen, specialist
- Email: kalemnaz@gmail.com
- Phone: +90 0312 797 00 00
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.