Iptacopan for Adult C3 Glomerulopathy in Spain

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study characterizes patient profiles and clinical experiences of iptacopan treatment in adult C3G patients who were given access through a Spain-based early access program between 2020 and 2025. It focuses on real-world use, including dosing and outcomes, in routine clinical settings. No formal comparative or interventional endpoints are specified in the description. Data are collected from multiple Spanish investigational sites affiliated with Novartis.

Why it matters

Who can join: the full rules

Inclusion criteria:

1. Adult patients (≥18 years).
2. Biopsy-confirmed C3G.
3. Patients who have received at least one dose of iptacopan through an EAP from October 2020 to June 2025.

Exclusion criteria:

1\. Patients treated with iptacopan through an EAP for indications other than C3G.

Where it's running

• Novartis Investigative Site
  Córdoba, Spain Recruiting
• Novartis Investigative Site
  Madrid, Spain Recruiting

Study contacts

• Study coordinator: Novartis Pharmaceuticals
• Email: novartis.email@novartis.com
• Phone: +41613241111

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• XEP527 in stable schizophrenia: safety and how it behaves in the body

  This small, early-stage study tests the safety and how XEP527 behaves in people with stable schizophrenia who are on a single antipsychotic.

  Recruiting Phase 1 Novartis · Bentonville, Arkansas · NCT07908680

• BTK inhibitor remibrutinib in hidradenitis suppurativa shows how it works in adults

  This phase 1 trial tests whether remibrutinib can safely affect HS in adults with moderate to severe disease.

  Recruiting at 2 sites Phase 1 Novartis · San Diego, California and 1 other locations · NCT07855276

• Dose-finding test of YMI024 in adults with stable coronary artery disease and high hsCRP

  This study tests several doses of YMI024 to see if it reduces inflammation and is safe for adults with stable CAD and elevated hsCRP, compared to placebo.

  Recruiting at 23 sites Phase 2 Novartis · Fairhope, Alabama and 22 other locations · NCT07830719

• Remibrutinib and omalizumab-based treatment approach for adults with chronic spontaneous urticaria not well controlled by antihistamines

  This trial tests a sequencing plan using remibrutinib and omalizumab to see if it helps adults with chronic spontaneous urticaria that isn’t well controlled by second-generation antihistamines.

  Recruiting at 10 sites Phase 3 Novartis · London, Ontario and 9 other locations · NCT07816328

• Single-dose combination therapy for uncomplicated malaria in young children

  This study tests whether a single oral dose of a combination of anti-malarial drugs can cure uncomplicated Plasmodium falciparum malaria in children aged 2 to under 12 years, compared with standard Coartem treatment.

  Recruiting at 5 sites Phase 2 Novartis · Banfora and 12 other locations · NCT07811908

• Remibrutinib for Severe Chronic Pruritus of Unknown Origin in Adults

  We’re testing whether remibrutinib can help adults with severe, unexplained itching that hasn’t gone away with moisturizers.

  Recruiting at 12 sites Phase 3 Novartis · Fremont, California and 11 other locations · NCT07811869

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.