Investigational imaging for monitoring treatment response in thyroid cancer and head and neck malignancies

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial evaluates the use of hyperpolarized magnetic resonance imaging (hpMRI) to predict treatment responses in patients with thyroid cancer and other head and neck malignancies undergoing radiation and/or systemic therapy. Participants will receive hpMRI scans at baseline and one week after treatment initiation, allowing researchers to assess early metabolic changes. The study aims to gather pilot data on the effectiveness of hpMRI in guiding treatment decisions for these patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Be willing and able to provide informed consent
* Be informed of the investigational nature of this study
* Be diagnosed with thyroid cancer and other malignancies of the head and neck with intent for treatment

Exclusion Criteria:

* Have a history of severe claustrophobia
* Have electrically, magnetically or mechanically activated implants that would preclude magnetic resonance imaging (MRI)
* Have a history of cardiac arrhythmia
* Have an allergy to Gadavist intravenous contrast
* Estimated glomerular filtration rate (eGFR) \< 30
* If female, be pregnant or breast feeding at time of consent

Where it's running

• M D Anderson Cancer Center
  Houston, Texas, United States Recruiting

Study contacts

• Principal investigator: Stephen Y Lai — M.D. Anderson Cancer Center
• Study coordinator: Stephen Y Lai
• Email: sylai@mdanderson.org
• Phone: 713-792-6528

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.