Investigation of lung valves in patients with emphysema or COPD

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the biological mechanisms behind the fibrotic and granulation responses that can limit the effectiveness of bronchoscopic lung volume reduction (BLVR) treatment using endobronchial valves in patients with severe COPD. By analyzing tissue and blood samples from patients eligible for EBV treatment, the study seeks to gain insights into how these biological responses affect the longevity of the treatment. The findings could help improve future interventions and patient outcomes in managing COPD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Elidgible for EBV treatment

Exclusion Criteria:

* Anticoagulation which cannot be stopped prior to the procedure

Where it's running

• University Medical Center Groningen
  Groningen, Netherlands Recruiting

Study contacts

• Principal investigator: Dirk-Jan Slebos, MD PhD — UMC-Groningen/NL
• Study coordinator: Dirk-Jan Slebos, MD PhD
• Email: d.j.slebos@umcg.nl
• Phone: +31503616161

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.