Investigating voice and brain responses in teachers with vocal fatigue

Neurobiological and Psychobiological Signatures of Vocal Effort in Early Career Teachers

Not applicable Interventional University Hospital, Bonn · NCT06126627

This study is testing how stress affects the voices and speech of early career female teachers with vocal fatigue to see if their brain and muscle responses are different from those without vocal fatigue.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment100 (estimated)
Ages21 Years to 39 Years
SexFemale
SponsorUniversity Hospital, Bonn Academic / other
Locations1 site (Bonn)
Trial IDNCT06126627 on ClinicalTrials.gov

What this trial studies

This study examines the impact of stress on voice control and speech in early career female teachers and student teachers experiencing vocal fatigue. Participants will undergo stress induction and perform speech tasks while their brain activity, voice muscle activity, and psychobiological responses are measured. The goal is to compare the reactivity patterns of those who respond to stress with those who do not, alongside control participants without vocal fatigue. This research aims to uncover the underlying causes of primary muscle tension dysphonia and its effects on quality of life.

Who should consider this trial

Good fit: Ideal candidates are female teachers or student teachers aged 21 to 39 with symptoms of vocal fatigue.

Not a fit: Patients with known vocal fold changes, respiratory illnesses, or psychological disorders may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved diagnostic and therapeutic approaches for voice disorders in teachers.

How similar studies have performed: While studies on voice disorders exist, this specific approach focusing on stress reactivity in teachers is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Teachers (max. 10 years full-time) or student teachers in good health between 21 and 39 years with symptoms of vocal fatigue.

Control participants in good health between 21 and 39 years without symptoms of vocal fatigue.

Exclusion Criteria:

* Lefthandedness
* Smoking (past 5 years)
* Known changes of the vocal folds (e.g., vocal fold nodules), vocal fold paralysis, surgeries on the larynx or thryoid or current organic or neurological changes of the vocal folds or vocal function per videoendoscopy and -stroboscopy of the larynx
* History of voice therapy
* Hoarseness
* Respiratory illness, allergies (respiratory, silver), reflux or asthma at time of participation
* Hearing disorder or hearing aids
* Psychological, neurological or endocrinological disorders
* Psychotropic or steorid medications
* Body mass index \> 30
* Indications against MRI such as metail parts in or on the body (e.g., permanent dental prostheses or braces, screws, prostheses, piercings or large tattoos
* Nearsightedness \> -5 diopters, if only glasses are worn
* Claustrophobia
* Pregnancy

Where this trial is running

Bonn

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Voice DisordersVoice Fatiguevoice disordersvocal fatigueoccupational voice disordersstress reactivityvocal controllaryngeal motor cortex
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.