Investigating vitreous degeneration after cataract surgery
The Incidence of Complete Posterior Vitreous Degeneration After Phacoemulsification
This study is testing how common complete vitreous degeneration is after cataract surgery in people over 50 to see if better detection methods can help prevent related eye problems.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 92 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Khon Kaen University Academic / other |
| Locations | 1 site (Khon Kaen) |
| Trial ID | NCT04727398 on ClinicalTrials.gov |
What this trial studies
This study examines the incidence of complete posterior vitreous degeneration following phacoemulsification, a common cataract surgery. It utilizes wide-field optical coherence tomography (OCT) to detect and classify posterior vitreous detachment (PVD) and its complications more effectively than previous methods. By identifying risk factors associated with abnormal PVD, the study aims to enhance prevention strategies for related disorders. The research will involve cataract patients over 50 years old who have not previously shown complete PVD.
Who should consider this trial
Good fit: Ideal candidates are cataract patients aged over 50 scheduled for phacoemulsification without prior complete PVD.
Not a fit: Patients with secondary cataracts, ocular trauma history, or other significant ocular diseases may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved detection and prevention of complications related to posterior vitreous detachment in cataract surgery patients.
How similar studies have performed: While there have been studies on PVD detection post-surgery, this approach using advanced wide-field OCT is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Cataract patients who was scheduled for phacoemulsification * Age \>50 years * No complete PVD was detected by OCT * Can be taken the wide-field OCT images * Written informed consent Exclusion Criteria: * Secondary cataract) * History of ocular trauma or head trauma * Systemic diseases that can cause the intraocular problems such as connective tissue disease * History of other ocular diseases such as glaucoma, uveitis and vitreoretinal disorders * History of intraocular laser treatment * History of intraocular surgery such as intravitreal drug injection Withdrawal Criteria: * Intraoperative complications such as posterior capsular rupture and zonule dialysis * Postoperative complications such as vitreous hemorrhage and postoperative endophthalmitis * Undergo the intraocular surgery during the follow-up period * Receiving the intraocular laser treatment during the follow-up period such as laser capsulotomy and panretinal photocoagulation * Having the ocular trauma or head trauma during the follow-up period
Where this trial is running
Khon Kaen
- Khon Kaen University — Khon Kaen, Thailand (Recruiting)
Study contacts
- Principal investigator: Suthasinee Sinawat, MD — KKU Eye Center, Department of Ophthalmology, Faculty of Medicine, Khon Kaen University
- Study coordinator: Suthasinee Sinawat, MD
- Email: ssuthasinee@kku.ac.th
- Phone: +66 81 5454594
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.