Clinical trial Recruiting at 1 site Interventional Ages 18 to 40

Investigating urine concentration after inhaling salmeterol

Official title: Urinary Concentration After Salmeterol in Well-trained Men and Females

Run by University of Copenhagen · NCT06657547 · Data updated 2026-11-12

This study is testing how inhaling salmeterol affects urine concentration in healthy adults aged 18-40 after they exercise.

Quick facts

Study typeInterventional
Ages18 Years to 40 Years
SexAll
Enrollment24 (estimated)
SponsorUniversity of Copenhagen
Academic / other
Locations1 site (Copenhagen)
StatusRecruiting
StartedOctober 31, 2024
Main results expectedDecember 31, 2026
Study endsDecember 31, 2026
Registry record updatedApril 9, 2025
Trial IDNCT06657547 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are healthy, physically active adults aged 18-40 who engage in more than 5 hours of exercise per week.

Probably not a fit

Patients who are smokers, have chronic illnesses, or are pregnant may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project aims to examine how inhalation of salmeterol affects urine concentration in healthy individuals. The study will assess urine samples following acute physical activity under both normal and heated conditions. Participants will be physically active adults aged 18-40 with high levels of oxygen uptake. The study will involve controlled inhalation of salmeterol and subsequent urine analysis to understand the drug's effects on hydration and concentration.

Why it matters

Potential benefit: If successful, this study could provide insights into the effects of salmeterol on hydration status and urinary concentration, potentially influencing treatment approaches for conditions requiring beta2-adrenergic stimulation.

How similar studies have gone: While there may be studies on salmeterol's effects, this specific investigation into urinary concentration after inhalation during physical activity appears to be novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inclusion Criteria:
* Age 18-40
* Physically active \>5 hours a week
* Maximum oxygen uptake classified as high or very high

Exclusion Criteria:

* Active smoker currently or within the past 5 years
* Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women)
* Chronic or acute illness deemed by the responsible study physician to affect the test parameters
* Deviation from the study protocol
* Lean mass index \>21 kg/m²
* Pregnancy
* Smoker
* Blood donation during the past 3 months

Where it's running

  • August Krogh Building
    Copenhagen, Denmark
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.