Investigating urine concentration after inhaling salmeterol
Official title: Urinary Concentration After Salmeterol in Well-trained Men and Females
Run by University of Copenhagen · NCT06657547 · Data updated 2026-11-12
This study is testing how inhaling salmeterol affects urine concentration in healthy adults aged 18-40 after they exercise.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 40 Years |
| Sex | All |
| Enrollment | 24 (estimated) |
| Sponsor | University of Copenhagen Academic / other |
| Locations | 1 site (Copenhagen) |
| Status | Recruiting |
| Started | October 31, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | April 9, 2025 |
| Trial ID | NCT06657547 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are healthy, physically active adults aged 18-40 who engage in more than 5 hours of exercise per week.
✕Probably not a fit
Patients who are smokers, have chronic illnesses, or are pregnant may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This project aims to examine how inhalation of salmeterol affects urine concentration in healthy individuals. The study will assess urine samples following acute physical activity under both normal and heated conditions. Participants will be physically active adults aged 18-40 with high levels of oxygen uptake. The study will involve controlled inhalation of salmeterol and subsequent urine analysis to understand the drug's effects on hydration and concentration.
Why it matters
Potential benefit: If successful, this study could provide insights into the effects of salmeterol on hydration status and urinary concentration, potentially influencing treatment approaches for conditions requiring beta2-adrenergic stimulation.
How similar studies have gone: While there may be studies on salmeterol's effects, this specific investigation into urinary concentration after inhalation during physical activity appears to be novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Inclusion Criteria: * Age 18-40 * Physically active \>5 hours a week * Maximum oxygen uptake classified as high or very high Exclusion Criteria: * Active smoker currently or within the past 5 years * Regular intake of medication deemed by the responsible study physician to affect the test parameters (hormonal contraception is accepted for women) * Chronic or acute illness deemed by the responsible study physician to affect the test parameters * Deviation from the study protocol * Lean mass index \>21 kg/m² * Pregnancy * Smoker * Blood donation during the past 3 months
Where it's running
-
August Krogh Building
Copenhagen, Denmark Recruiting
Study contacts
- Study coordinator: Morten Hostrup, PhD
- Email: mhostrup@nexs.ku.dk
- Phone: +4535321595
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.