Investigating treatment mechanisms for chronic neck pain
Specific and Shared Mechanisms Associated With Physical Therapy Interventions
This study is testing how different physical therapy treatments for chronic neck pain, like manual therapy and resistance exercise, can help people feel better and improve their daily activities.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 126 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Duke University Academic / other |
| Locations | 1 site (Charleston, South Carolina) |
| Trial ID | NCT05940012 on ClinicalTrials.gov |
What this trial studies
This study explores how different physical therapy treatments, specifically manual therapy and resistance exercise, affect outcomes for individuals with chronic neck pain. It aims to identify both specific treatment mechanisms unique to each approach and shared mechanisms that may be common across various interventions. The research will involve patients aged 18 and older who have experienced chronic neck pain for at least three months. By comparing these mechanisms, the study seeks to enhance understanding of how these treatments work and their effectiveness in alleviating pain and disability.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older with chronic neck pain lasting three months or more.
Not a fit: Patients with cervical pain and suspected radicular symptoms or a history of neck surgery within the past year may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to more effective treatment strategies for chronic neck pain, improving patient outcomes.
How similar studies have performed: Other studies have shown success in understanding treatment mechanisms for chronic pain, but this specific comparison of manual therapy and resistance exercise is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Individuals with chronic neck pain (chronic pain is defined using the International Association of the Study of Pain (IASP) pragmatic criteria of pain lasting for 3 months or more that cannot be attributed to another diagnosis or condition.) * 18 years of age and older * experience ongoing neck pain of ≥3 on a 10-point scale for most days of the previous 3-months. Exclusion Criteria: * Individuals with cervical pain and suspected radicular symptoms * a history of neck surgery within 1 year * current or suspected red flags * unable to speak or write in English.
Where this trial is running
Charleston, South Carolina
- The Medical University of South Carolina — Charleston, South Carolina, United States (Recruiting)
Study contacts
- Principal investigator: Chad E Cook — Duke University
- Study coordinator: Chad E Cook, PhD
- Email: chad.cook@dm.duke.edu
- Phone: 1 919 684 8905
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.