Investigating tibial tubercle osteotomy's role in knee ligament reconstruction

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the impact of tibial tubercle osteotomy (TTO) on the outcomes of medial patellofemoral ligament reconstruction (MPFL-R) in patients experiencing recurrent lateral patellofemoral instability. The study will randomly assign participants to receive either an isolated MPFL-R or an MPFL-R combined with TTO, focusing on patients with an increased tibial tubercle-trochlear groove (TT-TG) distance. The trial will assess feasibility in terms of patient recruitment, adherence to protocols, and follow-up completion rates over a minimum of 12 months post-surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age 13-30 years
* Symptomatic recurrent lateral patellofemoral instability
* TT-TG ≥15mm measured on MRI or ≥18mm on CT scan
* Closed physes (confirmed on knee x-rays)

Exclusion Criteria:

* Caton-Deschamps ratio ≥ 1.4 on lateral radiographs
* Femoral anteversion ≥ 25 degrees on diagnostic imaging rotational profile
* Tibial external rotation ≥ 45 degrees on diagnostic imaging rotational profile
* High-grade trochlear dysplasia requiring trochleoplasty
* Significant osteoarthritis on skyline plain imaging (Kellgren Lawrence grade ≥ 2)
* A chondral lesion of the patellofemoral joint that is undergoing a cartilage restoration procedure.
* Unable to complete computer-based outcome questionnaires
* Pregnant (at time of surgery)

Where it's running

• Banff Sport Medicine
  Canmore, Alberta, Canada Recruiting

Study contacts

• Principal investigator: Laurie A Hiemstra, MD, PhD — University of Calgary
• Study coordinator: Laurie A Hiemstra, MD, PhD
• Email: hiemstra@banffsportmed.ca
• Phone: 403 760 2897

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.