Clinical trial Recruiting at 1 site Observational Ages 18 to 50

Investigating the Upper Trapezius Muscle's Role in Chronic Shoulder Pain

Official title: Structure and Function of the Upper Trapezius and Its Role in Chronic Shoulder Pain: an Investigation of Kinematics, Morphology, Muscle Quality and Activation Distribution

Run by National Yang Ming Chiao Tung University · NCT06472349 · Data updated 2026-11-12

This study looks at how the upper trapezius muscle works in people with chronic shoulder pain compared to healthy individuals to see how muscle quality and other factors might affect their pain.

More Shoulder Pain trials

Quick facts

Study typeObservational
Ages18 Years to 50 Years
SexAll
Enrollment100 (estimated)
SponsorNational Yang Ming Chiao Tung University
Academic / other
Locations1 site (Taipei)
StatusRecruiting
StartedDecember 12, 2023
Main results expectedDecember 2026
Study endsDecember 2026
Registry record updatedApril 14, 2026
Trial IDNCT06472349 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates include individuals aged 18-50 with unilateral, non-traumatic chronic shoulder pain lasting more than three months.

Probably not a fit

Patients with a history of significant shoulder trauma or recent shoulder dislocation may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study examines the structure and function of the upper trapezius muscle in individuals suffering from chronic shoulder pain. It aims to explore how factors such as muscle morphology, activation distribution, and psychosocial elements like fear avoidance beliefs influence muscle activation during functional movements. By comparing patients with chronic shoulder pain to healthy controls, the study seeks to identify the interplay between muscle quality and various pain-related characteristics. The findings could help bridge existing gaps in understanding the upper trapezius muscle's role in chronic shoulder pain.

Why it matters

Potential benefit: If successful, this study could lead to improved treatment strategies for patients with chronic shoulder pain by enhancing understanding of muscle activation and related factors.

How similar studies have gone: While there is existing research on muscle activation and chronic pain, this specific investigation into the upper trapezius muscle's morphology and its relationship with chronic shoulder pain is relatively novel.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Chronic shoulder pain group

  * 18-50 years old18-50 years old
  * unilateral and non-traumatic shoulder pain
  * pain duration longer than 3 months
  * pain intensity more than VAS=2 during movement
  * presence 3 of 5 positive pain provocation tests: Hawkins-Kennedy test, Jobe test, or Neer's test Painful Arc, and Resistance Test against External Rotation.
* Healthy control group

  * presenting no shoulder pain at rest or during daily activities
  * negative results of the pain provocation test: Hawkins-Kennedy test, Jobe test, Neer's test, Painful Arc, Resistance Test against External Rotation and Spurling's neck compression test.

Exclusion Criteria:

\- Chronic shoulder pain group

* history of significant shoulder trauma, such as fracture or ultrasonography clinically suspected full thickness cuff tear
* recent shoulder dislocation in the last 2 years
* diagnosis of adhesive capsulitis characterized by a gradual and painful loss of both active and passive ROM in all shoulder planes, primarily external rotation
* shoulder pain originating from the cervical spine by using Spurling's neck compression test
* shoulder pain owing to the following disorders: arthritis (e.g., rheumatoid arthritis, osteoarthritis of shoulder complex), neurologic (e.g., stroke), neoplastic (e.g., breast cancer). and/or referred pain (e.g., visceral referred pain)
* corticoid injections over the shoulder during 6 months prior to the study
* history of shoulder and neck surgery

Where it's running

  • National Yang Ming Chiao Tung University
    Taipei, Taiwan
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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  • Movement-and-thinking therapy versus exercise for chronic shoulder pain

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  • Intralesional vs. Perilesional 5% Dextrose Injections for Partial Rotator Cuff Tears

    This trial tests whether injecting 5% dextrose directly into the tear or around it helps people with partial rotator cuff tears improve shoulder pain and function.

    Recruiting Ankara City Hospital Bilkent · Ankara · NCT07688902

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.