Investigating the role of magnesium in cognitive function after stroke
Official title: Relationship Between Magnesium Concentration in Blood and Kognitive Functions After Stroke
Run by BDH-Klinik Hessisch Oldendorf · NCT05132517 · Data updated 2026-11-12
This study is trying to see if magnesium levels affect thinking skills in people who have had a stroke, by looking at their cognitive abilities during and after their hospital stay.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 80 (estimated) |
| Sponsor | BDH-Klinik Hessisch Oldendorf Academic / other |
| Locations | 1 site (Hessisch Oldendorf, Lower Saxony) |
| Status | Recruiting |
| Started | October 26, 2022 |
| Main results expected | December 31, 2026 |
| Study ends | September 30, 2027 |
| Registry record updated | April 20, 2026 |
| Trial ID | NCT05132517 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are individuals who have experienced either ischemic or hemorrhagic strokes and can provide written consent.
✕Probably not a fit
Patients with pre-existing cognitive impairments, dementia, or significant mental disorders prior to the stroke may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the relationship between magnesium concentration and cognitive impairments in stroke patients. It will assess stroke severity and cognitive abilities using various scales during the initial hospital stay and follow-up assessments at 4 weeks and 3 months post-admission. The study will include both ischemic and hemorrhagic stroke patients, evaluating their magnesium levels and cognitive performance over time. Additionally, MRI scans will be conducted to measure the attention network of the patients.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of cognitive impairments in stroke patients through magnesium supplementation.
How similar studies have gone: While the relationship between magnesium levels and cognitive function in stroke patients has not been extensively studied, similar investigations in other contexts have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * ischemic/hemmorhagic stroke * written consent form Exclusion Criteria: * pre-existing dementia or cognitive impairment before stroke onset * pre-existing mental disorder (depression) or present/prior long-term treatment (\> 6 months) with psychotropic drugs * pre-existing malign tumor disease * participation in another clinical trial within the past 30 days * pregnancy or breastfeeding
Where it's running
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Institute for Neurorehabilitation Research, BDH-Clinic Hessich Oldendorf
Hessisch Oldendorf, Lower Saxony, Germany Recruiting
Study contacts
- Principal investigator: Simone B Schmidt, Dr. — BDH-Clinic Hessisch Oldendorf
- Study coordinator: Simone B Schmidt, Dr.
- Email: si.schmidt@nkho.de
- Phone: 0049 5152 781 215
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.