Investigating the Role of Foods in Familial Mediterranean Fever Attacks

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to explore the potential relationship between dietary triggers, particularly gluten and wheat, and the exacerbation of Familial Mediterranean Fever (FMF) attacks. It will involve patients diagnosed with FMF who will complete questionnaires to assess their dietary habits and any associated symptoms. The study seeks to clarify whether certain foods contribute to the frequency or severity of FMF episodes, which could lead to better dietary recommendations for affected individuals.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients, of both sexes, aged between 6 months and 80 years, affected by FMF, classified according to the Eurofever/PRINTO criteria.
* Patients able to understand and complete the questionnaires independently (or, in the case of pediatric ones, analyzed through the answers provided by parents).

Exclusion Criteria:

* Patients aged \<6 months and \>80 years.
* Patients unable to provide informed consent or complete the questionnaires.

Where it's running

• University Hospital of Palermo
  Palermo, Sicily, Italy Recruiting

Study contacts

• Study coordinator: Pasquale Mansueto, MD
• Email: pasquale.mansueto@unipa.it
• Phone: 3477279879

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Canakinumab use in FMF and Still's disease patients across real-world care

  This real-world study looks at how people with FMF or Still's disease who were treated with canakinumab fare over at least 6 months.

  Recruiting Novartis · Basel · NCT07517250

• Mediterranean diet with or without aerobic exercise for women with familial Mediterranean fever and fatty liver

  This trial will test whether adding regular aerobic exercise to a Mediterranean diet helps women with familial Mediterranean fever who have non-alcoholic fatty liver disease.

  Recruiting Cairo University · Dokki, Giza Governorate · NCT07130318

• Whole-body vibration plus vitamin D for adolescent girls with familial Mediterranean fever

  This project will try adding regular whole-body vibration sessions to vitamin D and usual colchicine for girls aged 13–17 with familial Mediterranean fever to see if it improves fitness, muscle strength, and bone mass.

  Recruiting Cairo University · Giza, Dokki · NCT07130305

• Inspiratory muscle training for adolescents with Familial Mediterranean Fever

  This trial will try a daily inspiratory muscle training program to see if it improves breathing strength, exercise tolerance, and fatigue in teenagers (ages 13–17) with Familial Mediterranean Fever who are taking colchicine.

  Recruiting Cairo University · Giza, Dokki · NCT07129538

• Testing an ancient grain for patients with non-celiac wheat sensitivity

  This study is testing if an ancient grain called Triticum monococcum is easier for people with non-celiac wheat sensitivity to tolerate compared to regular wheat.

  Recruiting University of Palermo · Palermo, Sicily · NCT06191432

• Using RPH-104 to prevent fever attacks in patients with Familial Mediterranean Fever who can't tolerate colchicine

  This study is testing if RPH-104 can help adults with Familial Mediterranean Fever who can’t take colchicine by preventing their fever attacks over a long period.

  Recruiting at 8 sites Phase 2 R-Pharm · Yerevan and 7 other locations · NCT05190991

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.