Investigating the role of Butyrophilins in colon cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to quantify BTNL molecules in patients with colon cancer to determine their potential as prognostic markers. It involves analyzing the status of BTN and BTNL in patients who are undergoing surgery for non-metastatic or synchronous metastatic colon cancer. The study will include patients who have a performance status of 0 or 1 and have provided informed consent. The goal is to better understand the relationship between these molecules and cancer prognosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient is older than 18 years old,
* Signed participation consent,
* Non-metastatic colon cancer immediately resectable or metastatic and liver synchronous for which it was decided a combined colic and liver surgery (metastatic patient at the outset) in multidisciplinary consultation meeting.
* Performance Status (PS) 0 or 1
* affiliated to the social security or beneficiary

Exclusion Criteria:

* Rectal cancer, colon cancer recurrence
* Emergency of colon cancer Surgery
* History of inflammatory disease of the digestive tract (Crohn's disease or ulcerative colitis)
* Patient who received neoadjuvant therapy other than chemotherapy
* Patient treated with immune-suppressors or long-course corticosteroids \<12 months
* Pregnant women or likely to be pregnant (without effective contraception) or breastfeeding,
* Person in urgent situation, person under legal protection measure, or unable to express his / her consent,
* Impossibility of submitting to the medical examination of the test for geographical, social or psychological reasons

Where it's running

• Institut Paoli-Calmettes
  Marseille, France Recruiting

Study contacts

• Study coordinator: Jihane PAKRADOUNI, PharmD,PhD
• Email: drci.up@ipc.unicancer.fr
• Phone: 04 91 22 37 78

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.