Investigating the risk of venous thrombosis in hospitalized medical patients
Incidence and Risk Factors of Venous Thrombosis of the Lower Limbs After Hospitalization in Medical Patients at Risk
This study looks at whether patients who are hospitalized for more than two days due to serious medical issues develop blood clots in their legs after they go home.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 2000 (estimated) |
| Ages | 18 Years to 90 Years |
| Sex | All |
| Sponsor | University of Monastir Academic / other |
| Locations | 1 site (Monastir) |
| Trial ID | NCT05512923 on ClinicalTrials.gov |
What this trial studies
This observational study aims to assess the incidence of venous thrombosis of the lower limbs in patients who have been hospitalized for more than 48 hours due to acute medical illnesses. It involves a systematic screening of patients six weeks after their discharge to identify both symptomatic and subclinical cases of thrombosis. The study is designed to gather data that could inform thromboprophylactic strategies based on the observed incidence and severity of this complication. Ethical approval has been obtained, and all participants will provide informed consent.
Who should consider this trial
Good fit: Ideal candidates are adults aged 40 and older who have been hospitalized for more than 48 hours due to acute medical conditions and are at risk for venous thrombosis.
Not a fit: Patients hospitalized for less than 48 hours or those with pre-existing conditions requiring anticoagulation may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved prevention strategies for venous thrombosis in at-risk hospitalized patients.
How similar studies have performed: Other studies have shown varying success in assessing venous thrombosis incidence in similar patient populations, but this specific approach in Tunisia is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * patients included adults aged at least 40 years old * hospitalized for more than 48 hours for an acute medical illness (i.e. heart failure, active cancer, acute ischemic stroke, infectious diseases, inflammatory disease and respiratory failure acute) * patients at risk of MIVT due to moderate or severe immobility, history of thrombophilia (factor C or S deficiency, etc.), body mass index of 30 kg/m2. Exclusion Criteria: * hospitalised for less than 48 * patients who required intensive care, patients with cognitive impairment, patients admitted for SARS-CoV-2 infection or patients with a hospital stay \<2 days, patients with a pre-existing reason for anticoagulation (therapeutic), such as atrial fibrillation or ETD and patients in whom MIVT is discovered on first ultrasound examination upon discharge from hospital.
Where this trial is running
Monastir
- Nouira — Monastir, Tunisia (Recruiting)
Study contacts
- Study coordinator: nouira semir, Pr
- Email: semir.nouira@rns.tn
- Phone: 73106000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.