Investigating the prevalence of carotid web in families
Official title: Family Screening for Internal Carotid Diaphragm Dysplasia (Carotid WEB): a Doppler Ultrasound Study
Run by University Hospital, Toulouse · NCT06336083 · Data updated 2026-11-12
This study is trying to find out how common carotid web is among family members of patients who have it, to see if there are any genetic links to this condition that can increase stroke risk.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years to 65 Years |
| Sex | All |
| Enrollment | 90 (estimated) |
| Sponsor | University Hospital, Toulouse Academic / other |
| Locations | 1 site (Toulouse) |
| Status | Recruiting |
| Started | September 11, 2024 |
| Main results expected | September 2027 |
| Study ends | September 2027 |
| Registry record updated | November 5, 2026 |
| Trial ID | NCT06336083 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include first-degree relatives of patients diagnosed with carotid web who are younger than 65 years old.
✕Probably not a fit
Patients who are not first-degree relatives of individuals with carotid web or those over the age of 65 may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to determine the prevalence of carotid web among first-degree relatives of patients diagnosed with carotid web using carotid duplex doppler ultrasound. Carotid web is a rare condition that poses a high risk of stroke, particularly in young adults, and its familial patterns have not been previously established. By examining relatives of affected individuals, the researchers hope to uncover potential genetic factors associated with this condition. The study will include 30 index patients and 60 relatives, all under the age of 65, at Toulouse University Hospital in France.
Why it matters
Potential benefit: If successful, this study could identify genetic predispositions to carotid web, leading to earlier detection and prevention strategies for at-risk individuals.
How similar studies have gone: While the familial aspects of carotid web have not been extensively studied, similar approaches in investigating genetic factors in other vascular conditions have shown promise.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: Carotid Web index patients: * Patients with carotid web confirmed by CT angiogram (CTA) of cervical arteries or digital substraction angiogram (DSA). * At least one first degree relative aged younger than 65 years old. Relatives patients : \- First degree relatives of patient with diagnosed carotid web. Exclusion Criteria: * Persons placed under judicial protection or under another protection status * Pregnant or breastfeeding woman.
Where it's running
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CHU de Toulouse, Purpan
Toulouse, France Recruiting
Study contacts
- Principal investigator: Claire VILLEPINTE, MD — University Hospital, Toulouse
- Study coordinator: Louis FONTAINE, MD
- Email: fontaine.l@chu-toulouse.fr
- Phone: 05 61 77 93 67
Similar studies
Other studies for the same condition or treatment. Recruiting studies are listed first.
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How common a carotid web is in people aged 15–25
This project will use neck duplex ultrasound to see how often a carotid web appears in people aged 15 to 25.
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.