Investigating the link between transient global amnesia and obstructive sleep apnea
Official title: PRevalence Of Transient Global Amnesia in Obstructive Sleep Apnea Syndrome
Run by University Hospital, Strasbourg, France · NCT06903026 · Data updated 2026-11-12
This study is trying to see if people with obstructive sleep apnea are more likely to experience transient global amnesia, which could help find new treatment options.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 250 (estimated) |
| Sponsor | University Hospital, Strasbourg, France Academic / other |
| Locations | 1 site (Strasbourg) |
| Status | Recruiting |
| Started | March 17, 2023 |
| Main results expected | December 2025 |
| Study ends | December 31, 2025 |
| Registry record updated | March 30, 2025 |
| Trial ID | NCT06903026 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include adults who have experienced an episode of transient global amnesia as defined by specific clinical criteria.
✕Probably not a fit
Patients with a history of recent head trauma or active epilepsy may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to explore the prevalence of transient global amnesia in patients diagnosed with obstructive sleep apnea syndrome. By analyzing a larger cohort of 200-250 patients, the study seeks to confirm or refute previous findings that suggested a potential association between these two conditions. The research will focus on understanding the underlying pathophysiological processes involved, which could lead to new therapeutic options. Participants will be recruited from the Neuropsychology Department of Strasbourg University Hospital based on specific inclusion criteria related to their amnestic episodes.
Why it matters
Potential benefit: If successful, this study could enhance our understanding of transient global amnesia and its relationship with sleep apnea, potentially leading to improved treatment strategies.
How similar studies have gone: Previous studies have suggested a link between obstructive sleep apnea and transient global amnesia, but this study aims to validate those findings on a larger scale.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Adult patients seen for consultation in the Neuropsychology Department of Strasbourg University Hospital between March 1, 2015 and December 31, 2021 following an episode of amnestic stroke meeting the Hodges and Warlow criteria: * The stroke must have been documented and reported by a competent witness present during the stroke. * Anterograde amnesia during the stroke. * Absence of vigilance, personality, and cognitive disorders other than memory disorders (aphasia, apraxia, etc.). * Absence of focal neurological symptoms during the episode and its aftermath. * Absence of epileptic manifestations. * Resolution of the episode in less than 24 hours. * Exclusion of patients with a history of recent head trauma or active epilepsy (undergoing regular treatment or having experienced a seizure in the last 2 years). * Subjects who have not expressed opposition to the reuse of their data for scientific research purposes. Exclusion Criteria: * Patients who have expressed opposition to the retrospective reuse of their data for scientific research purposes. * Patients with active epilepsy * Patients with recent head trauma * Patients with an MMS \< or equal to 25 * Subject under guardianship or curatorship * Subject under judicial protection
Where it's running
-
Service de Neurologie - CHU de Strasbourg - France
Strasbourg, France Recruiting
Study contacts
- Study coordinator: Benjamin CRETIN, MD
- Email: benjamin.cretin@chru-trasbourg.fr
- Phone: 33 3 88 12 86 34
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.