Investigating the link between Takotsubo Syndrome and air pollution
Takotsubo Syndrome and Air Pollution: the "Tako-Air" Study
This study is trying to see if air pollution is linked to Takotsubo Syndrome, a heart condition that can be triggered by stress or illness, to help understand how to prevent it better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 250 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Rome) |
| Trial ID | NCT05731830 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between air pollution and Takotsubo Syndrome (TTS), a condition characterized by acute myocardial injury often triggered by emotional stress or serious illness. The study will involve data extraction and clinical follow-up of patients diagnosed with TTS, focusing on their exposure to air pollutants. By analyzing this data, researchers hope to uncover potential risk factors and mechanisms that contribute to the severity and outcomes of TTS. The findings could enhance understanding of TTS and inform future prevention strategies.
Who should consider this trial
Good fit: Ideal candidates for this study are adults aged 18 and older who have been diagnosed with Takotsubo Syndrome and have available data on their exposure to air pollutants.
Not a fit: Patients under 18 years of age or those without available data on air pollution exposure may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could identify air pollution as a significant risk factor for Takotsubo Syndrome, leading to improved prevention and management strategies for patients.
How similar studies have performed: While the relationship between air pollution and cardiovascular conditions has been explored, this specific investigation into Takotsubo Syndrome is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age ≥18 years. * Diagnosis of TTS. * Available data for short-term and/or long-term exposure to air pollutants (see below). * Written informed consent to participate. Exclusion Criteria: * Age \<18 years. * Not available data for short-term and/or long-term exposure to air pollutants.
Where this trial is running
Rome
- Fondazione Policlinico Universitario A. Gemelli IRCCS — Rome, Italy (Recruiting)
Study contacts
- Principal investigator: Rocco A Montone, MD, PhD — Fondazione Policlinico Universitario Agostino Gemelli IRCCS
- Study coordinator: Rocco A Montone, MD, PhD
- Email: roccoantonio.montone@policlinicogemelli.it
- Phone: +39-0630154187
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.