Investigating the link between gut microbiota and prostate cancer risk
Prostate Metabolism, Cancer Risk and Gut Microbiota
This study is trying to see if changes in gut bacteria from diet and exercise can affect the risk of developing prostate cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 300 (estimated) |
| Ages | 18 Years and up |
| Sex | Male |
| Sponsor | Turku University Hospital Government |
| Locations | 2 sites (Turku and 1 other locations) |
| Trial ID | NCT06116851 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between gut microbiota and the risk of developing prostate cancer. It will involve multiple cohorts and utilize various interventions, including MRI scans, laboratory visits, and tissue sampling from prostate biopsies and surgeries. The study seeks to understand how lifestyle factors, particularly diet and physical activity, may influence prostate cancer risk through changes in gut microbiota composition. By analyzing these associations, the research hopes to shed light on potential mechanisms of prostate carcinogenesis.
Who should consider this trial
Good fit: Ideal candidates for this study are men who are at risk for prostate cancer or have been diagnosed with prostate hyperplasia.
Not a fit: Patients who are unable or unwilling to comply with study procedures may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to new insights into prostate cancer prevention and management through lifestyle modifications.
How similar studies have performed: While some studies have explored the role of gut microbiota in cancer therapy responses, the specific investigation of its impact on prostate cancer risk is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Provision of signed and dated informed consent form. * Ability and stated willingness to comply with all study procedures and availability for the duration of the study. Exclusion Criteria: * inability to comply with study procedures or unwillingness to participate in the study.
Where this trial is running
Turku and 1 other locations
- University of Turku — Turku, Finland (Recruiting)
- Turku University Hospital — Turku, Finland (Recruiting)
Study contacts
- Principal investigator: Peter J. Bostrom, MD, PhD — Turku University Hospital and University of Turku
- Study coordinator: Peter J. Bostrom, MD, PhD
- Email: peter.bostrom@tyks.fi
- Phone: +358-2-3135925
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.