Investigating the link between glucose, lipids, and brain aging
A Prospective Cohort Study on the Associations of Endocrine Glucose & Lipids With Brain Aging-related Conditions in Chinese Men and Women
This study looks at whether problems with sugar and fat levels in the body can affect brain health and lead to memory issues in people aged 50 and older.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 10000 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | Shandong Provincial Hospital Government |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT06066775 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between glucose and lipid metabolism and brain aging-related conditions, such as mild cognitive impairment, in a community-based population aged 50 and older. A survey will be conducted involving 10,000 participants from various geographic regions to assess whether abnormalities in glucose and lipid levels are risk factors for cognitive decline. The study will not involve any interventions but will focus on gathering data to better understand these metabolic factors in relation to brain health.
Who should consider this trial
Good fit: Ideal candidates for this study are individuals aged 50 years and older who are willing to provide informed consent and comply with study requirements.
Not a fit: Patients with a history of neurological or psychiatric conditions that affect cognitive function, or those with major systemic diseases, may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could provide insights into metabolic risk factors for cognitive decline, potentially leading to preventive strategies for brain aging-related conditions.
How similar studies have performed: While the relationship between metabolism and brain aging has been explored, this specific approach of a large community-based observational study is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age \>= 50 years old; 2. Gender: males and females; 3. Provide written informed consent; 4. Satisfactory compliance. Exclusion Criteria: 1. Pregnant or lactating women 2. No history of addiction or neurological, psychiatric, or systemic diseases known to affect cognitive function, including head trauma, subdural hematoma, current depression, and epilepsy 3. Any other condition or major systemic diseases that the investigator feels would interfere with trial participation or evaluation of results.
Where this trial is running
Jinan, Shandong
- Shandong Provincial Hospital Affiliated to Shandong First Medical University — Jinan, Shandong, China (Recruiting)
Study contacts
- Study coordinator: Ling Gao
- Email: gaoling1@medmail.com.cn
- Phone: +8613793187189
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.