Investigating the link between biological rhythms and metabolism
Association Between Serum Metabolism Markers and Biological Rhythm
Shandong Provincial Hospital · NCT03669809
This study is trying to see how our body’s natural rhythms affect metabolism and whether this connection can help us understand metabolic disorders better.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 18 Years to 30 Years |
| Sex | All |
| Sponsor | Shandong Provincial Hospital (other gov) |
| Locations | 1 site (Jinan, Shandong) |
| Trial ID | NCT03669809 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore how biological rhythms, particularly circadian rhythms, influence metabolism in humans. It focuses on the role of clock genes and their feedback loops in regulating metabolic processes in various organs, including the liver and intestine. By examining the relationship between these rhythms and metabolic disorders, the study seeks to enhance our understanding of physiological homeostasis. Participants will be monitored for their metabolic responses in relation to their biological rhythms.
Who should consider this trial
Good fit: Ideal candidates for this study are healthy males and females aged 18 to 30 years old.
Not a fit: Patients with hormonal disorders, significant health issues, or those on specific medications may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved management strategies for metabolic disorders by aligning treatment with biological rhythms.
How similar studies have performed: While the study explores a well-known concept, the specific association between biological rhythms and metabolism in humans is still being actively researched, indicating a mix of established knowledge and novel inquiry.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Male or female； * Aged of 18 to 30 years old; Exclusion Criteria: * Presence of pituitary/hypothalamic disorders, polycystic ovarian syndrome， thyroid disorders, hypertension, malignant tumor, cardiac insufficiency，hepatic or renal insufficiency, gastrointestinal disorders and acute infection; * Receiving psychotropic or hormonal medications including hormonal contraception and hormone therapies; * Taking lipid-lowering agents or hypoglycemic agents and other drugs that known to influence cardiovascular health; * Pregnancy or lactation women; * Obviously poor compliance.
Where this trial is running
Jinan, Shandong
- Shandong Provincial Hospital — Jinan, Shandong, China (RECRUITING)
Study contacts
- Study coordinator: Ling Gao
- Email: gaoling1@medmail.com.cn
- Phone: +86 53168776910
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Rhythm Nodal, Metabolism and Nutrition Disorder, Metabolism Disorder, Lipid, biological rhythm, metabolism, hormone, lipid, bile acids