Investigating the impact of sleep on fertility during embryo transfer
Sleep Length and Euploid Embryo Transfer Prospective Study
This study is testing if better sleep can improve fertility outcomes for women undergoing in vitro fertilization with embryo transfers.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 150 (estimated) |
| Ages | 18 Years to 45 Years |
| Sex | Female |
| Sponsor | Northwestern University Academic / other |
| Locations | 1 site (Chicago, Illinois) |
| Trial ID | NCT06139757 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the relationship between sleep quality and fertility outcomes in women undergoing in vitro fertilization with euploid embryo transfers. Participants will wear a wireless device on their finger to monitor sleep patterns in the weeks leading up to and following the embryo transfer. The findings from this study could provide insights into how improving sleep may enhance fertility outcomes and inform future therapeutic strategies for infertility. By focusing on the often-overlooked aspect of sleep, the study seeks to address a significant gap in reproductive health research.
Who should consider this trial
Good fit: Ideal candidates for this study are women undergoing their first, second, or third euploid frozen embryo transfer.
Not a fit: Patients with specific conditions such as polycystic ovary syndrome, high BMI, or a history of multiple miscarriages may not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved fertility outcomes for women undergoing embryo transfers by highlighting the importance of sleep.
How similar studies have performed: While the impact of sleep on fertility is a relatively novel area of research, other studies have suggested potential benefits of sleep quality on reproductive health, indicating a promising avenue for further exploration.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Undergoing a single euploid frozen embryo transfer * Patient's 1st, 2nd, or 3rd embryo transfer (prior fresh or frozen transfers included) Exclusion Criteria: * Primary infertility diagnosis of polycystic ovary syndrome * BMI \> 40 * Diagnosis of primary ovarian insufficiency (FSH \> 40) * Night work * High risk of poor outcomes of fertility treatment \[\> 2 prior miscarriages (women with recurrent pregnancy loss), significant uterine factor infertility \[\>/= 2 myomectomies (open abdominal or laparoscopic) or any non-hystoeroscopic myomectomy entering the endometrial cavity\] * Undergoing medical fertility preservation for a significant medical co-morbidity * Current cancer diagnosis * \> 3 prior failed embryo transfers in attempt for current live birth
Where this trial is running
Chicago, Illinois
- Northwestern Memorial Hospital — Chicago, Illinois, United States (Recruiting)
Study contacts
- Principal investigator: Jessica Walter, MD, MSCE — Northwestern University
- Study coordinator: Sarah C Cromack, MD
- Email: sarah.capelouto@nm.org
- Phone: 312-926-8244
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.