Investigating the impact of bypass and cross-clamp times on heart surgery outcomes

Impact of the Cardiopulmonary Bypass and Cross-Clamp Time Ratio on Postoperative Outcomes in Open Heart Surgery: A Prospective Observational Analysis

Observational Kocaeli City Hospital · NCT06873620

This study looks at how the time spent on heart-lung machines and the time the heart is stopped during surgery affects recovery and complications for patients having open heart surgery.

Quick facts

Study typeObservational
Enrollment300 (estimated)
Ages18 Years to 80 Years
SexAll
SponsorKocaeli City Hospital Government
Locations1 site (Kocaeli, Izmit)
Trial IDNCT06873620 on ClinicalTrials.gov

What this trial studies

This observational study aims to explore how the ratio of cardiopulmonary bypass (CPB) time to cross-clamp (CC) time affects postoperative complications in patients undergoing open heart surgery. By analyzing the relationship between these two time metrics, the study seeks to identify potential correlations with outcomes such as bleeding, acute kidney injury, and other complications. The research will involve patients who are scheduled for on-pump open heart surgery, providing valuable insights into surgical practices and patient care.

Who should consider this trial

Good fit: Ideal candidates for this study are patients scheduled for elective open heart surgery requiring cardiopulmonary bypass.

Not a fit: Patients undergoing emergency open heart surgery or those having surgery on a beating heart may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved surgical protocols that minimize postoperative complications for heart surgery patients.

How similar studies have performed: While studies have linked CPB and CC times to complications, this specific ratio has not been previously explored, making this approach novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients undergoing open heart surgery
* Undergo on pump surgery

Exclusion Criteria:

* Patients undergoing emergency open heart surgery Patients undergoing open heart surgery on a beating heart

Where this trial is running

Kocaeli, Izmit

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions CABGCardiac AnesthesiaCardiac Surgery PrognosisBypass ComplicationOn-pump Valve Surgery or CABGAnesthesiaon-pump cabgcardiac anesthesia
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.