Investigating the EGFR gene in lung cancer patients
Utilizing Long-read Sequencing to Investigate the EGFR Landscape of EGFR Positive Lung Cancer Patients
This study is testing how the EGFR gene is different in people with EGFR positive lung cancer compared to healthy individuals to better understand the risk of developing this type of cancer.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 100 Years |
| Sex | Female |
| Sponsor | Our Lady of the Lake Hospital Academic / other |
| Locations | 1 site (Baton Rouge, Louisiana) |
| Trial ID | NCT06659458 on ClinicalTrials.gov |
What this trial studies
This observational study aims to explore the EGFR gene landscape in patients diagnosed with EGFR positive lung cancer and compare it with healthy individuals. By collecting blood samples and performing gene sequencing, researchers will assess the genetic variations associated with EGFR mutations. The study seeks to validate a DNA instability model that estimates the risk of developing cancer-linked mutations, potentially providing insights into susceptibility to EGFR positive lung cancer and other cancer types.
Who should consider this trial
Good fit: Ideal candidates include biologically born females aged 18-100 who have been diagnosed with EGFR positive lung cancer or healthy individuals without a cancer diagnosis.
Not a fit: Patients who are biologically born male or those under 18 years of age will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding of genetic susceptibility to lung cancer, aiding in early detection and prevention strategies.
How similar studies have performed: While the approach of utilizing long-read sequencing for genetic analysis is gaining traction, this specific application to the EGFR landscape in lung cancer is relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 18-100 years old * Biologically born female * Diagnosed with EGFR positive lung cancer (Arm 1-Cancer group) * No cancer diagnosis (Arm 2-health control) Exclusion Criteria: * less than 18 years of age * Biologically born male * Incarcerated at the time of participation
Where this trial is running
Baton Rouge, Louisiana
- Our Lady of the Lake Regional Medical Center — Baton Rouge, Louisiana, United States (Recruiting)
Study contacts
- Study coordinator: Cynthia Knox, MBA
- Email: Cynthia.Knox@fmolhs.org
- Phone: 225-765-3344
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.